CAS 63660-21-9

Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-5-bromo-2'-deoxy-

Description:

Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-5-bromo-2'-deoxy- is a modified nucleoside derivative that incorporates both uridine and a complex aromatic substituent. This compound features a uridine backbone, which is a nucleoside composed of a ribose sugar and a uracil base, modified at the 5' position with a bis(4-methoxyphenyl)phenylmethyl group. The presence of the bromine atom at the 5-position of the uracil moiety introduces additional reactivity and potential for biological activity. The methoxy groups on the aromatic rings enhance the lipophilicity of the compound, potentially influencing its interaction with biological membranes and receptors. Such modifications can affect the compound's stability, solubility, and overall pharmacological properties. This substance may be of interest in biochemical research, particularly in studies related to nucleic acid chemistry, drug design, or as a potential therapeutic agent. However, specific biological activities and applications would require further investigation through experimental studies.

Formula: C₃₀H₂₉BrN₂O₇

5’-O-(4,4’-Dimethoxytrityl)-5-bromo-2’-deoxyuridine

Controlled Product

CAS: 63660-21-9

Formula: C₃₀H₂₉BrN₂O₇

Color and Shape: Neat

Molecular weight: 609.46

Ref: TR-D460765

5-Bromo-2'-deoxy-5'-O-DMT-uridine 3'-CE phosphoramidite

CAS: 63660-21-9

5-Bromo-2'-deoxy-5'-O-DMT-uridine 3'-CE phosphoramidite is a nucleoside analog and a potential anticancer drug. It is an excellent monophosphate, which can be used as a building block for synthesis of DNA. 5-Bromo-2'-deoxy-5'-O-DMT-uridine 3'-CE phosphoramidite has antiviral activity against HIV and herpes simplex virus, as well as antifungal activity against Candida albicans. This compound has also been shown to have antitumor activity in vitro in the presence of other anticancer drugs.

Formula: C₃₉H₄₆BrN₄O₈P

Purity: Min. 95%

Molecular weight: 809.7 g/mol

Ref: 3D-PB09116