CAS 63676-25-5

[6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[2-(1-pyrrolidinyl)ethoxy]phenyl]methanone

Description:

The chemical substance known as [6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[2-(1-pyrrolidinyl)ethoxy]phenyl]methanone, with the CAS number 63676-25-5, is a complex organic compound characterized by its multi-functional structure. It features a benzo[b]thien moiety, which contributes to its potential biological activity, along with hydroxyl groups that may enhance solubility and reactivity. The presence of a pyrrolidinyl group suggests potential interactions with biological targets, possibly influencing pharmacological properties. This compound may exhibit properties such as antioxidant activity, and its structural components indicate potential applications in medicinal chemistry, particularly in the development of therapeutic agents. Its synthesis and characterization would typically involve advanced organic chemistry techniques, and its behavior in biological systems would be of interest for further research. As with many organic compounds, its stability, solubility, and reactivity can vary based on environmental conditions and the presence of other substances.

Formula: C₂₇H₂₅NO₄S

InChI: InChI=1/C27H25NO4S/c29-20-7-3-19(4-8-20)27-25(23-12-9-21(30)17-24(23)33-27)26(31)18-5-10-22(11-6-18)32-16-15-28-13-1-2-14-28/h3-12,17,29-30H,1-2,13-16H2

InChI key: InChIKey=JLERVPBPJHKRBJ-UHFFFAOYSA-N

SMILES: C(=O)(C1=C(SC=2C1=CC=C(O)C2)C3=CC=C(O)C=C3)C4=CC=C(OCCN5CCCC5)C=C4

Synonyms:

• Ly-117018
• Methanone, [6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-
• [6-Hydroxy-2-(4-Hydroxyphenyl)-1-Benzothiophen-3-Yl]{4-[2-(Pyrrolidin-1-Yl)Ethoxy]Phenyl}Methanone
• [6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[2-(1-pyrrolidinyl)ethoxy]phenyl]methanone
• Ly 139478
• Phenethipylone
• 6-Hydroxy-2-(4-hydroxyphenyl)benzo(B)thien-3-yl 4-(2-(1-pyrrolidinyl)ethoxy) phenyl ketone
• Lilly 117018
• [6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl][4-[2-(1-pyrrolidinyl)ethoxy]phenyl]methanone
• [6-hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]-[4-(2-pyrrolidin-1-ylethoxy)phenyl]methanone

LY 117018

Controlled Product

CAS: 63676-25-5

Formula: C₂₇H₂₅NO₄S

Color and Shape: Neat

Molecular weight: 459.557

Ref: TR-L485000

LY117018

CAS: 63676-25-5

LY117018 shows antiproliferative effects on breast cancer cell lines. LY117018 is a Raloxifene analog and is a selective estrogen receptor modulator.

Formula: C₂₇H₂₅NO₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 459.56

Ref: TM-T15800

LY 117018

CAS: 63676-25-5

LY 117018 is a dopamine analog that binds to the toll-like receptor and blocks the production of proinflammatory cytokines. LY 117018 also inhibits epidermal growth factor (EGF) in liver cells and cyclin D2, which is involved in cell cycle regulation. This drug has been shown to be effective in a model system using fetal bovine serum with angiogenic factors, such as vascular endothelial growth factor (VEGF). The effect on blood vessels was dose-dependent for LY 117018. This drug potentiates the actions of 17β-estradiol on mcf-7 cells and serum prolactin levels are significantly decreased in vivo by this compound.

Formula: C₂₇H₂₅NO₄S

Purity: Min. 95%

Molecular weight: 459.6 g/mol

Ref: 3D-NCA67625