CAS 637-58-1

Pramoxine hydrochloride

Description:

Pramoxine hydrochloride is a local anesthetic commonly used for its analgesic properties in topical formulations. It is characterized by its ability to block nerve signals in the area where it is applied, providing temporary relief from pain and itching. The substance appears as a white to off-white crystalline powder and is soluble in water, which facilitates its use in various pharmaceutical preparations. Pramoxine hydrochloride has a relatively low toxicity profile, making it suitable for over-the-counter products, particularly in formulations for skin irritations, hemorrhoids, and insect bites. Its mechanism of action involves the inhibition of sodium channels, which prevents the propagation of nerve impulses. Additionally, it is often combined with other active ingredients to enhance its efficacy and provide a broader spectrum of relief. As with any medication, it is essential to follow recommended dosages and consult healthcare professionals for appropriate use, especially in sensitive populations such as children or individuals with specific health conditions.

Formula: C₁₇H₂₈ClNO₃

InChI: InChI=1/C17H27NO3.ClH/c1-2-3-12-20-16-5-7-17(8-6-16)21-13-4-9-18-10-14-19-15-11-18;/h5-8H,2-4,9-15H2,1H3;1H

InChI key: InChIKey=SYCBXBCPLUFJID-UHFFFAOYSA-N

SMILES: O(CCCN1CCOCC1)C2=CC=C(OCCCC)C=C2.Cl

Synonyms:

• 4-[3-(p-Butoxyphenoxy)propyl]morpholine hydrochloride
• Morpholine, 4-[3-(4-butoxyphenoxy)propyl]-, hydrochloride (1:1)
• Morpholine, 4-[3-(p-butoxyphenoxy)propyl]-, hydrochloride
• Pramacort
• Pramocaina, Clorhidrato
• Pramocaine Hydrochloride
• Pramocaine, Chlorhydrate
• Pramocainhydrochlorid
• Pramoxine hydrochloride
• Proctofoam
• Tronolaine
• Tronothan
• Tronothane
• Tronothane hydrochloride
• Pramoxine HCL
• Praxomine Hydrochloride
• 4-(3-(p-butoxyphenoxy)propyl)-morpholinhydrochloride
• 4-[3-(4-butoxyphenoxy)propyl]morpholine Hydrochloride (1:1)
• 4-N-BUTOXYPHENYL G-MORPHOLINOPROPYL ETHER Hydrochloride
• gamma-morpholinopropyl4-n-butoxyphenyletherhydrochloride
• p-butoxyphenylgamma-morpholinopropyletherhydrochloride
• Morpholine, 4-[3-(4-butoxyphenoxy)propyl]-, hydrochloride
• 4-n-butoxyphenyl gamma-morpholinopropyl ether hydrochloride
• PRAMOXINEHYDROCHLORIDE,USP
• 4-[3-(P-BUTOXYPHENOXY)PROPYL]MORPHOLINE HYDROCHLORIDE USP
• Proxazocaine hydrochloride
• MORPHOLINE,4-(3-(PARA-BUTOXYPHENOXY)PROPYL)-,HYDROCHLORIDE
• PRAMOXINE HCL USP
• TRONOTHANE HYDROCHLORIDE USP

Pramoxine Hydrochloride

CAS: 637-58-1

Color and Shape: Neat

Ref: 61-FOR3228.00

Pramoxine Hydrochloride

CAS: 637-58-1

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₁₇H₂₇NO₃·HCl

Color and Shape: White Powder

Molecular weight: 329.17577

Ref: 45-1554002

Morpholine, 4-[3-(4-butoxyphenoxy)propyl]-, hydrochloride

CAS: 637-58-1

Formula: C₁₇H₂₈ClNO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 329.8621

Ref: IN-DA00IB9C

Pramocaine hydrochloride

CAS: 637-58-1

Pramocaine hydrochloride (Pramoxine HCl), a topical anesthetic, is served as an antipruritic.

Formula: C₁₇H₂₇NO₃·HCl

Purity: 99.15% - 99.61%

Color and Shape: Crystals White Or Off White Crystalline Powder

Molecular weight: 329.86

Ref: TM-T0460

Pramoxine HCl

CAS: 637-58-1

Formula: C₁₇H₂₇NO₃·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 293.41 36.46

Ref: 4Z-P-907

4-(3-(4-Butoxyphenoxy)Propyl)Morpholine Hydrochloride

CAS: 637-58-1

4-(3-(4-Butoxyphenoxy)Propyl)Morpholine Hydrochloride

Purity: 98%

Molecular weight: 329.86g/mol

Ref: 54-OR1030428

Pramoxine-d9 HCl

CAS: 637-58-1

Formula: C₁₇H₁₈D₉NO₃·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 302.46 36.46

Ref: 4Z-P-906

Pramocaine hydrochloride

CAS: 637-58-1

Pramocaine hydrochloride

Purity: ≥98%

Molecular weight: 329.86g/mol

Ref: 54-BUP18157

Pramoxine hydrochloride

Controlled Product

CAS: 637-58-1

Formula: C₁₇H₂₇NO₃·ClH

Color and Shape: Neat

Molecular weight: 329.86

Ref: 04-C16286230

Pramoxine Hydrochloride

CAS: 637-58-1

Formula: C₁₇H₂₇NO₃·ClH

Color and Shape: Neat

Molecular weight: 329.86

Ref: 86-MM3228.00

Pramoxine Hydrochloride

Controlled Product

CAS: 637-58-1

Applications Pramoxine Hydrochloride is used as a local anaesthetic and often in anti-itch formulations.
References Young, T. et al.: J. Derm. Treat., 20, 76 (2009); Schmidt, A. et al.: Pharm. Res.. 22. 2121 (2005);

Formula: C₁₇H₂₇NO₃·ClH

Color and Shape: Off-White

Molecular weight: 329.86

Ref: TR-P700850

PRAMOXINE HYDROCHLORIDE

CAS: 637-58-1

Purity: 98%;RG

Molecular weight: 329.8699951

Ref: 10-F818579

Pramoxine-d9

Controlled Product

CAS: 637-58-1

Applications Pramoxine-d9 is the isotope labelled analog of Pramoxine (P700850); used as a local anaesthetic and often found in anti-itch formulations.
References Young, T. et al.: J. Derm. Treat., 20, 76 (2009); Schmidt, A. et al.: Pharm. Res.. 22. 2121 (2005)

Formula: C₁₇D₉H₁₈NO₃

Color and Shape: Neat

Molecular weight: 302.457

Ref: TR-P700852

Pramoxine HCl

CAS: 637-58-1

Pramoxine HCl is a leukotriene receptor antagonist that inhibits the action of the enzyme phospholipase A2, which is responsible for the conversion of arachidonic acid to prostaglandin H2. Pramoxine HCl has been shown to inhibit skin cell proliferation and induce apoptosis in human skin cells. It also has anti-inflammatory properties, and may have therapeutic potential for treating autoimmune diseases such as Crohn's disease. Pramoxine HCl is a colorless liquid that has a particle size of less than 10 microns, and has an odor of benzalkonium chloride. The melting point of pramoxine is 203°C, and its boiling point is 390°C.

Formula: C₁₇H₂₇NO₃·HCl

Purity: Min. 95%

Molecular weight: 329.86 g/mol

Ref: 3D-AAA63758