CAS 637-87-6
:1-Chloro-4-iodobenzene
Description:
1-Chloro-4-iodobenzene, with the CAS number 637-87-6, is an aromatic halogenated compound characterized by the presence of both chlorine and iodine substituents on a benzene ring. Specifically, the chlorine atom is located at the para position relative to the iodine atom, which influences the compound's reactivity and physical properties. This substance typically appears as a colorless to pale yellow liquid or solid, depending on temperature and purity. It is moderately soluble in organic solvents such as ethanol and ether but has limited solubility in water due to its hydrophobic aromatic structure. 1-Chloro-4-iodobenzene is used in organic synthesis, particularly in the preparation of various pharmaceuticals and agrochemicals, as well as in coupling reactions. The presence of both halogens allows for diverse reactivity patterns, making it a valuable intermediate in chemical synthesis. However, it should be handled with care due to potential toxicity and environmental concerns associated with halogenated compounds.
Formula:C6H4ClI
InChI:InChI=1S/C6H4ClI/c7-5-1-3-6(8)4-2-5/h1-4H
InChI key:InChIKey=GWQSENYKCGJTRI-UHFFFAOYSA-N
SMILES:ClC1=CC=C(I)C=C1
Synonyms:- 1-Chlor-4-iodbenzol
- 1-Cloro-4-Iodobenceno
- 4-Chloro-1-iodobenzene
- 4-Chloroiodobenzene
- 4-Chlorophenyl iodide
- 4-Iodo-1-chlorobenzene
- 4-Iodochlorobenzene
- Benzene, 1-chloro-4-iodo-
- Ethyl Hydrazinylacetate
- Nsc 32862
- P-Chloroiodobenzene
- p-Chlorophenyl iodide
- p-Iodochlorobenzene
- p-Iodophenyl chloride
- See more synonyms
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Found 9 products.
1-Chloro-4-iodobenzene
CAS:Formula:C6H4ClIPurity:>99.0%(GC)Color and Shape:White to Yellow to Orange powder to crystalMolecular weight:238.451-Chloro-4-iodobenzene, 99%
CAS:<p>This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci</p>Formula:C6H4ClIPurity:99%Color and Shape:White to pale cream, Crystals or powder or crystalline powder or fused solidMolecular weight:238.451-Chloro-4-iodobenzene
CAS:Formula:ClC6H4IPurity:≥ 98.0%Color and Shape:White to yellow crystalsMolecular weight:238.454-Chloroiodobenzene
CAS:4-ChloroiodobenzeneFormula:C6H4ClIPurity:≥95%Color and Shape: white crystalline solidMolecular weight:238.45343g/mol1-Chloro-4-iodobenzene
CAS:<p>1-Chloro-4-iodobenzene is a crystalline compound that can be used in the synthesis of palladium complexes. It reacts with amines to form aryl halides, which are useful intermediates for the synthesis of a variety of organic compounds. The reaction mechanism for 1-chloro-4-iodobenzene and amines is an electrophilic substitution reaction, which involves a nucleophilic attack by the amine on the carbon atom adjacent to the halogen atom. Halides are introduced as reagents in this reaction because they are nucleophiles. The reaction is thermodynamically favorable and efficient because 1-chloro-4-iodobenzene has a high concentration of iodine atoms, which react with the amine to form an intermediate diazonium salt. This salt then reacts with trifluoroacetic acid to produce the desired product and hydrogen iodide.</p>Formula:C6H4ClIPurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:238.45 g/mol4-Chloroiodobenzene
CAS:Controlled Product<p>Applications 4-Chloroiodobenzene is used as a reagent in the synthesis of Clothiapine (C588550); an atypical antipsychotic of the dibenzothiazepine chemical class that has shown efficacy in treatment-resistant schizophrenic patients.<br>References Schmutz, J., et al.: Helvetica Chimica Acta 50, 245 (1967); Geller, V., et al.: Schizophrenia Research 80 (2-3), 343 (2005)<br></p>Formula:C6H4ClIColor and Shape:NeatMolecular weight:238.45
