CAS 63701-55-3

Benzenepropanoic acid, β-(aminomethyl)-4-chloro-, hydrochloride (1:1), (βR)-

Description:

Benzenepropanoic acid, β-(aminomethyl)-4-chloro-, hydrochloride (1:1), (βR)-, is a chemical compound characterized by its structure, which includes a benzene ring, a propanoic acid moiety, and an aminomethyl group with a chlorine substituent at the para position. This compound is typically encountered as a hydrochloride salt, which enhances its solubility in water and facilitates its use in various applications. The presence of the amino group suggests potential for biological activity, making it of interest in pharmaceutical research. The specific stereochemistry indicated by (βR) denotes the configuration of the chiral center, which can influence the compound's biological interactions and pharmacological properties. As a hydrochloride, it is likely to exhibit properties typical of amine salts, such as increased stability and ease of handling. Overall, this compound's unique functional groups and structural features contribute to its potential utility in medicinal chemistry and related fields.

Formula: C₁₀H₁₂ClNO₂·ClH

InChI: InChI=1S/C10H12ClNO2.ClH/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14;/h1-4,8H,5-6,12H2,(H,13,14);1H/t8-;/m0./s1

InChI key: InChIKey=WMNUVYYLMCMHLU-QRPNPIFTSA-N

SMILES: [C@H](CC(O)=O)(CN)C1=CC=C(Cl)C=C1.Cl

Synonyms:

• (+)-Baclofen hydrochloride
• (R)-4-Amino-3-(4-chlorophenyl)butanoic acid hydrochloride
• (R)-4-Amino-3-(4-chlorophenyl)butyric acid hydrochloride
• (R)-Baclofen monohydrochloride
• Benzenepropanoic acid, beta-(aminomethyl)-4-chloro-, (betaR)-, hydrochloride (1:1)
• Benzenepropanoic acid, β-(aminomethyl)-4-chloro-, hydrochloride (1:1), (βR)-
• Benzenepropanoic acid, β-(aminomethyl)-4-chloro-, hydrochloride, (R)-
• Benzenepropanoic acid, β-(aminomethyl)-4-chloro-, hydrochloride, (βR)-
• R-Baclofen hydrochloride
• d-Baclofen hydrochloride
• (3R)-4-Amino-3-(4-chlorophenyl)butanoic acid hydrochloride (1:1)

R(+)-Baclofen hydrochloride

CAS: 63701-55-3

Formula: C₁₀H₁₃Cl₂NO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 250.1217

Ref: IN-DA00E9LT

R(+)-Baclofen hydrochloride

CAS: 63701-55-3

Formula: C₁₀H₁₂ClNO₂·HCl

Molecular weight: 250.12

Ref: 7W-GL3932

R(+)-Baclofen.Hydrochloride

CAS: 63701-55-3

M01381 - R(+)-Baclofen.Hydrochloride

Formula: C₁₀H₁₃Cl₂NO₂

Purity: >98%

Molecular weight: 250.12

Ref: 10-M01381

R(+)-Baclofen.Hydrochloride

Controlled Product

CAS: 63701-55-3

R(+)-Baclofen.Hydrochloride is a GABA analogue that stimulates the GABA-benzodiazepine receptor complex and produces antinociception. It has been shown to be effective against diabetic neuropathy in rats, with no observed side effects. R(+)-Baclofen.Hydrochloride is used for the treatment of trigeminal neuralgia, butyric acid induced hyperalgesia and chronic constriction injury in rats. The main mechanism of action of R(+)-Baclofen.Hydrochloride is its ability to activate the benzodiazepine receptor by binding to it, which leads to mitochondrial membrane potential depolarization and an increase in the release of gamma-aminobutyric acid (GABA) from neurons.

Formula: C₁₀H₁₃Cl₂NO₂

Purity: Min. 95%

Molecular weight: 250.12 g/mol

Ref: 3D-NCA70155

(R)-Baclofen hydrochloride

CAS: 63701-55-3

Arbaclofen HCl, a GABA-B agonist, treats spasticity from spinal injury by reducing excitatory transmission.

Formula: C₁₀H₁₃Cl₂NO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 250.12

Ref: TM-T17306