CAS 63732-74-1

(5alpha,6beta)-6-methoxy-17-methyl-4,5-epoxymorphinan-3-ol

Description:

The chemical substance known as (5alpha,6beta)-6-methoxy-17-methyl-4,5-epoxymorphinan-3-ol, with the CAS number 63732-74-1, is a synthetic derivative of morphinan, a class of compounds that includes various opioids. This compound features a complex polycyclic structure characteristic of morphinans, with specific stereochemistry at the 5 and 6 positions, which influences its biological activity. The presence of a methoxy group at the 6 position and a methyl group at the 17 position contributes to its pharmacological properties. As an epoxide, it may exhibit unique reactivity and interactions with biological targets. This compound is of interest in medicinal chemistry, particularly for its potential analgesic effects and its role in the development of new therapeutic agents. Its specific interactions with opioid receptors and other biological pathways would require further investigation to fully understand its efficacy and safety profile. Overall, this substance exemplifies the complexity and potential of modified morphinan derivatives in drug development.

Formula: C₁₈H₂₃NO₃

InChI: InChI=1/C18H23NO3/c1-19-8-7-18-11-4-6-14(21-2)17(18)22-16-13(20)5-3-10(15(16)18)9-12(11)19/h3,5,11-12,14,17,20H,4,6-9H2,1-2H3/t11-,12+,14+,17-,18-/m0/s1

O6-Methyl-7,8-dihydro-6-isomorphine (1 mg/ml in Acetonitrile)

Controlled Product

CAS: 63732-74-1

Formula: C₁₈H₂₃NO₃

Color and Shape: Single Solution

Molecular weight: 301.38

Ref: TR-KIT5915

O6-Methyl-7,8-dihydro-6-isomorphine

Controlled Product

CAS: 63732-74-1

Applications O6-Methyl-7,8-dihydro-6-isomorphine is an impurity of Hydromorphone(H714650), an analgesic(narcotic).
References Buchwald, M.E., et al.: J. Pharmacol. Exp. Ther., 71, 197 (1941), Zernig, G., et al.: Life Sci., 57, 2113 (1995), Keith, D., et al.: J. Biol. Chem., 271, 19021 (1996), Pawar, M., et al.: Eur. J. Pharmacol., 563, 92 (2007)

Formula: C₁₈H₂₃NO₃

Color and Shape: Neat

Molecular weight: 301.38

Ref: TR-M302150

(O6-Methyl-d3)-7,8-dihydro-6-isomorphine

Controlled Product

CAS: 63732-74-1

Applications (O6-Methyl-d3)-7,8-dihydro-6-isomorphine is the labeled analogue of O6-Methyl-7,8-dihydro-6-isomorphine (M302150), an impurity of Hydromorphone(H714650).

Formula: C₁₈D₃H₂₀NO₃

Color and Shape: Neat

Molecular weight: 304.399

Ref: TR-M302152