CAS 6377-14-6

4H-Dibenzo[de,g]quinolin-11-ol, 5,6,6a,7-tetrahydro-10-methoxy-6-methyl-, hydrochloride (1:1), (6aR)-

Description:

4H-Dibenzo[de,g]quinolin-11-ol, 5,6,6a,7-tetrahydro-10-methoxy-6-methyl-, hydrochloride (1:1), (6aR)-, with CAS number 6377-14-6, is a chemical compound characterized by its complex polycyclic structure, which includes a dibenzoquinoline framework. This compound features a hydroxyl group (-OH) and a methoxy group (-OCH3), contributing to its potential biological activity. The presence of the tetrahydro moiety indicates that it has undergone partial hydrogenation, which can influence its reactivity and solubility. As a hydrochloride salt, it is typically more soluble in water compared to its free base form, enhancing its utility in pharmaceutical applications. The stereochemistry denoted by (6aR) suggests a specific three-dimensional arrangement of atoms, which can be crucial for its interaction with biological targets. Overall, this compound may exhibit interesting pharmacological properties, making it a subject of interest in medicinal chemistry and drug development. However, detailed studies would be necessary to fully elucidate its biological effects and potential applications.

Formula: C₁₈H₁₉NO₂·ClH

InChI: InChI=1S/C18H19NO2.ClH/c1-19-9-8-11-4-3-5-13-16(11)14(19)10-12-6-7-15(21-2)18(20)17(12)13;/h3-7,14,20H,8-10H2,1-2H3;1H/t14-;/m1./s1

InChI key: InChIKey=NIWCFXFECXNXGD-PFEQFJNWSA-N

SMILES: CN1[C@]2(C=3C(C=4C(C2)=CC=C(OC)C4O)=CC=CC3CC1)[H].Cl

Synonyms:

• (6aR)-11-hydroxy-10-methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium chloride
• 10-Methoxy-6a-beta-aporphin-11-ol hydrochloride
• 10-methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol
• 4H-Dibenzo(de,g)quinolin-11-ol, 5,6,6a,7-tetrahydro-10-methoxy-6-methyl-, hydrochloride, (R)- (9CI)
• 4H-Dibenzo[de,g]quinolin-11-ol, 5,6,6a,7-tetrahydro-10-methoxy-6-methyl-, hydrochloride (1:1), (6aR)-
• 4H-Dibenzo[de,g]quinolin-11-ol, 5,6,6a,7-tetrahydro-10-methoxy-6-methyl-, hydrochloride, (6aR)-
• 4H-Dibenzo[de,g]quinolin-11-ol, 5,6,6a,7-tetrahydro-10-methoxy-6-methyl-, hydrochloride, (R)-
• 6a-beta-Aporphin-11-ol, 10-methoxy-, monohydrochloride
• 6abeta-Aporphin-11-ol, 10-methoxy-, monohydrochloride (8CI)
• 6aβ-Aporphin-11-ol, 10-methoxy-, monohydrochloride
• Nsc 305238

R-(-)-Apocodeine hydrochloride

Controlled Product

CAS: 6377-14-6

Apocodeine hydrochloride is a natural product that is used in the treatment of cancer. It has been shown to have antiproliferative effects on cho-k1 cells, which are human colon carcinoma cells. Apocodeine hydrochloride also inhibits the production of dopamine in rat brain and has been shown to inhibit bromocriptine-induced prolactin release from rat pituitary cells in vitro. Apocodeine hydrochloride has been extensively studied in epidemiological studies and has been found to be effective against cancer, with no adverse side effects.

Formula: C₁₈H₂₀ClNO₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 317.81 g/mol

Ref: 3D-FA17953