CAS 63824-12-4

1-[(2Z)-2-(4-Chlorophenyl)-3-(2,4-dichlorophenyl)-2-propen-1-yl]-1H-imidazole

Description:

1-[(2Z)-2-(4-Chlorophenyl)-3-(2,4-dichlorophenyl)-2-propen-1-yl]-1H-imidazole, with CAS number 63824-12-4, is a chemical compound characterized by its imidazole ring, which is a five-membered heterocyclic structure containing two nitrogen atoms. This compound features a propenyl side chain that is substituted with chlorophenyl groups, contributing to its potential biological activity. The presence of multiple chlorine atoms enhances its lipophilicity and may influence its interaction with biological targets. Typically, compounds of this nature are studied for their pharmacological properties, including antimicrobial or antifungal activities. The geometric configuration indicated by the (2Z) notation suggests a specific stereochemistry that can affect the compound's reactivity and biological interactions. Overall, this compound exemplifies the complexity of synthetic organic chemistry, where modifications to the molecular structure can lead to significant changes in chemical behavior and potential applications in medicinal chemistry.

Formula: C₁₈H₁₃Cl₃N₂

InChI: InChI=1S/C18H13Cl3N2/c19-16-4-1-13(2-5-16)15(11-23-8-7-22-12-23)9-14-3-6-17(20)10-18(14)21/h1-10,12H,11H2/b15-9+

InChI key: InChIKey=WNGFKUOERJDDIY-OQLLNIDSSA-N

SMILES: C(=C\C1=C(Cl)C=C(Cl)C=C1)(\CN2C=CN=C2)/C3=CC=C(Cl)C=C3

Synonyms:

• (Z)-1-(2,4-Dichloro-beta-(p-chlorophenyl)cinnamyl)imidazole
• 1-[(2Z)-2-(4-Chlorophenyl)-3-(2,4-dichlorophenyl)-2-propen-1-yl]-1H-imidazole
• 1-[(2Z)-2-(4-chlorophenyl)-3-(2,4-dichlorophenyl)prop-2-en-1-yl]-1H-imidazole
• 1H-Imidazole, 1-[(2Z)-2-(4-chlorophenyl)-3-(2,4-dichlorophenyl)-2-propen-1-yl]-
• 1H-Imidazole, 1-[(2Z)-2-(4-chlorophenyl)-3-(2,4-dichlorophenyl)-2-propenyl]-
• 1H-Imidazole, 1-[2-(4-chlorophenyl)-3-(2,4-dichlorophenyl)-2-propenyl]-, (Z)-
• Aliconazol
• Aliconazol [INN-Spanish]
• Aliconazole [INN]
• Aliconazolum
• Aliconazolum [INN-Latin]
• Unii-51Hx72H34H

Aliconazole

CAS: 63824-12-4

Aliconazole is a triazole-based antifungal agent, which is a synthetic derivative developed through chemical synthesis. It functions by inhibiting the enzyme lanosterol 14α-demethylase, crucial in the biosynthesis of ergosterol, a vital component of fungal cell membranes. By disrupting ergosterol production, aliconazole compromises the structural integrity of the cell membrane, leading to increased permeability and eventual cell death.

Formula: C₁₈H₁₃Cl₃N₂

Purity: Min. 95%

Molecular weight: 363.7 g/mol

Ref: 3D-NCA82412

Aliconazole

CAS: 63824-12-4

Aliconazole is an imidazole derivative with antifungal activity for the study of skin infections.

Formula: C₁₈H₁₃Cl₃N₂

Purity: 99.21% - 99.79%

Color and Shape: Solid

Molecular weight: 363.67

Ref: TM-T14179