CAS 63854-31-9

1-[2-(Trifluoromethyl)phenyl]piperazine

Description:

1-[2-(Trifluoromethyl)phenyl]piperazine is an organic compound characterized by its piperazine core, which is a six-membered ring containing two nitrogen atoms. The presence of a trifluoromethyl group (-CF3) attached to a phenyl ring significantly influences its chemical properties, enhancing lipophilicity and potentially affecting its biological activity. This compound is typically colorless to pale yellow in appearance and is soluble in organic solvents. It is often studied for its pharmacological properties, particularly in the context of neuropharmacology, as piperazine derivatives can interact with various neurotransmitter systems. The trifluoromethyl group is known to increase metabolic stability and can modulate the compound's interaction with biological targets. Safety data indicates that, like many fluorinated compounds, it should be handled with care due to potential toxicity. Overall, 1-[2-(Trifluoromethyl)phenyl]piperazine is of interest in medicinal chemistry and drug development, particularly for its potential therapeutic applications.

Formula: C₁₁H₁₃F₃N₂

InChI: InChI=1S/C11H13F3N2/c12-11(13,14)9-3-1-2-4-10(9)16-7-5-15-6-8-16/h1-4,15H,5-8H2

InChI key: InChIKey=VZUBMIDXJRGARE-UHFFFAOYSA-N

SMILES: C(F)(F)(F)C1=C(C=CC=C1)N2CCNCC2

Synonyms:

• 1-(2-(Trifluoromethyl)Phenyl)Piperazine
• 1-(o-Trifluoromethylphenyl)piperazine
• 4-(2-Trifluoromethylphenyl)piperazine
• Piperazine, 1-[2-(trifluoromethyl)phenyl]-

1-(2-Trifluoromethylphenyl)piperazine

CAS: 63854-31-9

Formula: C₁₁H₁₃F₃N₂

Purity: >98.0%(GC)(T)

Color and Shape: Colorless to Light yellow clear liquid

Molecular weight: 230.23

Ref: 3B-T2739

1-(2-Trifluoromethylphenyl)piperazine

Controlled Product

CAS: 63854-31-9

1-(2-Trifluoromethylphenyl)piperazine is a chemical compound that is used as an analytical reagent and has shown to be a 5-HT1A receptor antagonist. It has also been shown to inhibit serotonin uptake, which may be the mechanism by which it inhibits the effects of serotonin in the brain. 1-(2-Trifluoromethylphenyl)piperazine is not active on 5-HT3 receptors, but can antagonize 5-HT4 and 5-HT2C receptors.

Formula: C₁₁H₁₃F₃N₂

Purity: Min. 95%

Molecular weight: 230.23 g/mol

Ref: 3D-FT99788