CAS 63877-76-9

3-[(1E)-2-(4-Hydroxyphenyl)ethenyl]phenol

Description:

3-[(1E)-2-(4-Hydroxyphenyl)ethenyl]phenol, also known by its CAS number 63877-76-9, is an organic compound characterized by its phenolic structure, which includes a hydroxyl group (-OH) attached to a phenyl ring. This compound features a vinyl group that connects two phenolic units, contributing to its potential as a chromophore and its ability to participate in various chemical reactions. It exhibits properties typical of phenolic compounds, such as antioxidant activity and the ability to form hydrogen bonds, which can influence its solubility and reactivity. The presence of the hydroxyl group enhances its polarity, making it more soluble in polar solvents. Additionally, this compound may exhibit biological activity, including potential applications in pharmaceuticals or as a dye, due to its structural characteristics. Its stability and reactivity can be influenced by environmental factors such as pH and temperature, making it of interest in both synthetic and applied chemistry contexts.

Formula: C₁₄H₁₂O₂

InChI: InChI=1S/C14H12O2/c15-13-8-6-11(7-9-13)4-5-12-2-1-3-14(16)10-12/h1-10,15-16H/b5-4+

InChI key: InChIKey=UFGKEFGYNRJIGO-SNAWJCMRSA-N

SMILES: C(=C/C1=CC(O)=CC=C1)\C2=CC=C(O)C=C2

Synonyms:

• Phenol, 3-[(1E)-2-(4-hydroxyphenyl)ethenyl]-
• 3-[(1E)-2-(4-Hydroxyphenyl)ethenyl]phenol
• Phenol, 3-[2-(4-hydroxyphenyl)ethenyl]-, (E)-

4-[(1E)-2-(3-Hydroxyphenyl)ethenyl]phenol

CAS: 63877-76-9

4-[(1E)-2-(3-Hydroxyphenyl)ethenyl]phenol is a metabolite of estrone sulfate. It is a potent estrogen that can be used in the treatment of prostate cancer, to inhibit the growth of cancer cells. 4-[(1E)-2-(3-Hydroxyphenyl)ethenyl]phenol has been shown to have antiestrogenic activity in breast cancer cell lines and to inhibit the formation of estrogen analogs in vitro. 4-[(1E)-2-(3-Hydroxyphenyl)ethenyl]phenol has been used as an estrogen receptor ligand in transfection experiments with human breast cancer cells, resulting in inhibition of target gene expression. The molecule also inhibits DNA polymerase activity and is believed to form carcinogenic nitrosamines and diazonium ions when subjected to nitrite and hydrogen peroxide. This molecule also exhibits weak antioxidant activity, which may be

Formula: C₁₄H₁₂O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 212.24 g/mol

Ref: 3D-NCA87776