CAS 6398-98-7: Amodiaquine dihydrochloride dihydrate

Description: Amodiaquine dihydrochloride dihydrate is a chemical compound primarily used as an antimalarial agent. It belongs to the class of 4-aminoquinoline derivatives and is structurally related to chloroquine. The substance appears as a white to off-white crystalline powder and is soluble in water, which facilitates its use in pharmaceutical formulations. Its molecular formula reflects the presence of two hydrochloride ions and two water molecules, indicating its dihydrochloride dihydrate form. Amodiaquine acts by interfering with the heme detoxification process in the malaria parasite, ultimately leading to its death. While effective against certain strains of Plasmodium, its use has been limited due to concerns over potential side effects, including hepatotoxicity and the risk of developing resistance. As with many antimalarial drugs, careful consideration of dosage and monitoring for adverse reactions is essential in clinical settings. Additionally, it is important to note that the compound should be handled with care, following appropriate safety guidelines due to its pharmacological properties.

Formula: C₂₀H₂₂ClN₃O·2ClH·2H₂O

InChI: InChI=1S/C20H22ClN3O.2ClH.2H2O/c1-3-24(4-2)13-14-11-16(6-8-20(14)25)23-18-9-10-22-19-12-15(21)5-7-17(18)19;;;;/h5-12,25H,3-4,13H2,1-2H3,(H,22,23);2*1H;2*1H2

InChI key: InChIKey=YVNAYSHNIILOJS-UHFFFAOYSA-N

SMILES: Cl.ClC=1C=CC=2C(=NC=CC2NC3=CC=C(O)C(=C3)CN(CC)CC)C1.O

Synonyms:

• 4-[(7-Chloroquinolin-4-Yl)Amino]-2-[(Diethylamino)Methyl]Phenol
• 4-[(7-Chloroquinolin-4-Yl)Amino]-2-[(Diethylamino)Methyl]Phenol Dihydrochloride
• 4-[(7-Chloroquinolin-4-Yl)Amino]-2-[(Diethylamino)Methyl]Phenol Dihydrochloride Dihydrate
• 5-[(7-Chloroquinolin-4-Yl)Amino]-2-[(Diethylamino)Methyl]Phenol Dihydrochloride
• Amodiaquin dihydrochloride dihydrate
• Amodiaquine dihydrochloride dihydrate
• AmodiaquineHydrochloride
• Phenol, 4-[(7-chloro-4-quinolinyl)amino]-2-[(diethylamino)methyl]-, dihydrochloride, dihydrate
• Phenol, 4-[(7-chloro-4-quinolinyl)amino]-2-[(diethylamino)methyl]-, hydrochloride, hydrate (1:2:2)
• o-Cresol, 4-[(7-chloro-4-quinolyl)amino]-α-(diethylamino)-, dihydrochloride, dihydrate

4-(7-Chloro-4-quinolinylamino)-2-(diethylaminomethyl)phenol dihydrochloride dihydrate, 98%

CAS: 6398-98-7

An anti-malarial quinoline derivative that acts as an histamine N-methyltransferase inhibitor This Thermo Scientific Chemicals …

• Formula: C₂₀H₂₂ClN₃O•2HCl·2H₂O
• Purity: 98%
• Molecular weight: 464.82 (392.33anhy)

Amodiaquine hydrochloride RS

CAS: 6398-98-7

Amodiaquine Hydrochloride

CAS: 6398-98-7

Drugs containing a quinoline or isoquinoline ring-system (whether or not hydrogenated) not further fused

• Formula: C₂₀H₂₂ClN₃O·2ClH·2H₂O
• Color and Shape: Yellow Crystalline Powder
• Molecular weight: 463.11962

Amodiaquine dihydrochloride dihydrate

CAS: 6398-98-7

Amodiaquine dihydrochloride dihydrate (Amodiaquin hydrochloride) is an orally active 4-aminoquinoline derivative with antimalarial and anti-inflammatory …

• Formula: C₂₀H₂₈Cl₃N₃O₃
• Purity: 99.97%
• Color and Shape: Solid
• Molecular weight: 464.82

Amodiaquin dihydrochloride dihydrate

CAS: 6398-98-7

• Formula: C₂₀H₂₈Cl₃N₃O₃
• Purity: 99%
• Color and Shape: Solid
• Molecular weight: 464.8136

Amodiaquin Dihydrochloride Dihydrate

CAS: 6398-98-7

• Purity: 99%
• Molecular weight: 464.81g/mol

Amodiaquine dihydrochloride dihydrate

CAS: 6398-98-7

• Purity: ≥98%
• Molecular weight: 464.82g/mol

Amodiaquin dihydrochloride dihydrate

CAS: 6398-98-7

• Formula: C₂₀H₂₂ClN₃O·2HCl·2H₂O
• Molecular weight: 464.81

Amodiaquine Dihydrochloride Dihydrate

CAS: 6398-98-769-44-3 86-42-0

• Formula: C₂₀H₂₂ClN₃O·2HCl·2H₂O
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Yellow to Orange powder to crystal
• Molecular weight: 464.81

Amodiaquine Dihydrochloride Dihydrate

CAS: 6398-98-7

• Formula: C₂₀H₂₂ClN₃OClHH₂O
• Color and Shape: Neat
• Molecular weight: 464.81

Amodiaquine Dihydrochloride Dihydrate

CAS: 6398-98-7

Applications Amodiaquine Dihydrochloride Dihydrate is a salt of Amiodiaquine (A634200), an antimalarial. References Natarajan, L., …

• Formula: C₂₀H₂₂ClN₃OClHH₂O
• Color and Shape: Neat
• Molecular weight: 464.81

Amodiaquine dihydrochloride dihydrate

CAS: 6398-98-7

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₂₀H₂₈Cl₃N₃O₃
• Color and Shape: Yellow, Crystalline powder
• Molecular weight: 464.81

4-([7-Chloro-4-quinolinyl]amino)-2-([diethylamino]methyl)phenol dihydrochloride dihydrate

CAS: 6398-98-7

4-([7-Chloro-4-quinolinyl]amino)-2-([diethylamino]methyl)phenol dihydrochloride dihydrate (BQCA) is a quinoline derivative that inhibits the growth of prostate cancer …

• Purity: Min. 95%