CAS 64-47-1

Pyrrolo[2,3-b]indol-5-ol, 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethyl-, 5-(N-methylcarbamate), (3aS,8aR)-, sulfate (2:1)

Description:

Pyrrolo[2,3-b]indol-5-ol, 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethyl-, 5-(N-methylcarbamate), (3aS,8aR)-, sulfate (2:1) is a complex organic compound characterized by its unique bicyclic structure, which includes a pyrrole and indole moiety. This compound is known for its potential biological activity, particularly in pharmacology, where it may exhibit properties such as antitumor or antimicrobial effects. The presence of the N-methylcarbamate group suggests that it may interact with biological systems through enzyme inhibition or receptor modulation. The sulfate moiety indicates that the compound may have increased solubility and bioavailability in aqueous environments. Its stereochemistry, denoted by the (3aS,8aR) configuration, is crucial for its biological activity, as the spatial arrangement of atoms can significantly influence how the molecule interacts with biological targets. Overall, this compound represents a class of substances that are of interest in medicinal chemistry and drug development due to their complex structure and potential therapeutic applications.

Formula: C₁₅H₂₁N₃O₂H₂O₄S

InChI: InChI=1S/C15H21N3O2.H2O4S/c1-15-7-8-17(3)13(15)18(4)12-6-5-10(9-11(12)15)20-14(19)16-2;1-5(2,3)4/h5-6,9,13H,7-8H2,1-4H3,(H,16,19);(H2,1,2,3,4)/t13-,15+;/m1./s1

InChI key: InChIKey=LLIODTIILSCNOH-PBCQUBLHSA-N

SMILES: S(=O)(=O)(O)O.C[C@]12C=3C(N(C)[C@]1(N(C)CC2)[H])=CC=C(OC(NC)=O)C3

Synonyms:

• (3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl methylcarbamate sulfate
• Eserine sulfate
• Eserine sulphate
• Physostigmine Sulphate
• Physostigmine hemisulfate
• Physostigmine sulfate
• Physostigmine, sulfate (2:1)
• Pyrrolo[2,3-b]indol-5-ol, 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethyl-, 5-(N-methylcarbamate), (3aS,8aR)-, sulfate (2:1)
• Pyrrolo[2,3-b]indol-5-ol, 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethyl-, methylcarbamate (ester), (3aS,8aR)-, sulfate (2:1) (salt)
• Pyrrolo[2,3-b]indol-5-ol, 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethyl-, methylcarbamate (ester), (3aS-cis)-, sulfate (2:1) (salt)
• bis{(3aS,8aS)-1,3a,8-trimethyl-5-[(methylcarbamoyl)oxy]-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-1-ium} sulfate

Eserine hemisulfate salt

CAS: 64-47-1

Formula: C₁₅H₂₁N₃O₂·5H₂SO₄

Purity: ≥ 95% (anhydrous basis)

Color and Shape: White to off-white powder

Molecular weight: 324.39

Ref: 7W-GL2953

Physostigmine Hemisulfate

CAS: 64-47-1

Formula: C₁₅H₂₁N₃O₂H₂O₄S

Molecular weight: 275.35 1/2*98.07

Ref: 4Z-P-213

Physostigmine Hemisulfate

Controlled Product

CAS: 64-47-1

Applications Physostigmine Hemisulfate is a parasympathomimetic, specifically, a reversible cholinesterase inhibitor obtained from the Calabar bean, used to treat glaucoma and delayed gastric emptying.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Engelhart, L., et al.: Arch. Exp. Pathol. Pharmakol., 150, 1 (1930); Muhtadi, F.J., et al.: Anal. Profiles Drug Subs., 18, 289 (1989)

Formula: C₁₅H₂₁N₃O₂·H₂O₄S

Color and Shape: Neat

Molecular weight: 648.77

Ref: TR-P398505

Physostigmine hemisulfate

CAS: 64-47-1

cholinesterase inhibitor

Formula: C₁₅H₂₁N₃₀₂H₂₀₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 324.39

Ref: TM-T23153

Eserine sulfate

CAS: 64-47-1

Eserine sulfate is a cholinergic drug that has been shown to inhibit the enzyme acetylcholinesterase, leading to an accumulation of acetylcholine. This can lead to increased muscle activity and cognitive function. Eserine sulfate could be used as a potential biomarker for leukemic mice and may have cytotoxic effects on cancer cells. The compound was also shown to have significant cytotoxicity in vitro against human leukemia cells.

Formula: C₃₀H₄₄N₆O₈S

Purity: Min. 95%

Molecular weight: 648.77 g/mol

Ref: 3D-FE71427