CAS 64-69-7

Iodoacetic acid

Description:

Iodoacetic acid is an organic compound with the molecular formula C2H2I2O2. It is a halogenated acetic acid derivative, characterized by the presence of iodine atoms, which significantly influence its chemical properties and reactivity. This compound typically appears as a white to off-white crystalline solid and is soluble in water and organic solvents. Iodoacetic acid is known for its role as a reagent in organic synthesis, particularly in the introduction of iodine into various organic molecules. It exhibits strong electrophilic characteristics due to the presence of the iodine atoms, making it useful in nucleophilic substitution reactions. Additionally, it has applications in biochemistry, particularly as a reagent for modifying proteins and enzymes, as it can react with thiol groups. However, it is important to handle iodoacetic acid with care due to its potential toxicity and irritant properties. Proper safety measures should be observed when working with this compound in laboratory settings.

Formula: C₂H₃IO₂

InChI: InChI=1S/C2H3IO2/c3-1-2(4)5/h1H2,(H,4,5)

InChI key: InChIKey=JDNTWHVOXJZDSN-UHFFFAOYSA-N

SMILES: C(CI)(O)=O

Synonyms:

• 2-Iodoacetic acid
• Acetic acid, 2-iodo-
• Acetic acid, iodo-
• Acide iodoacetique
• Acido Iodoacetico
• Ai3-52119
• Brn 1739079
• CH₂ICOOH
• Ccris 667
• Ch2Icooh
• Hsdb 4008
• IA
• Iodessigsaure
• Iodoacetate
• Iodoacetates
• Jodessigsaeure
• Kyselina jodoctova
• Kyselina jodoctova [Czech]
• MIA
• Monoiodine acetate
• Monoiodoacetate
• Monoiodoacetic acid
• Nsc 2125
• Iodoacetic acid

Iodoacetic acid, 97+%

CAS: 64-69-7

Iodoacetic acid is used as a reagent for the modification of sulfhydryl groups in organic synthesis. It reacts with cysteine moiety in proteins to prevent the re-formation of disulfide bonds during protein sequencing. It is also used as a general reagent in acylation reactions as well as in glycopep

Formula: C₂H₃IO₂

Purity: 97+%

Color and Shape: White to yellow to orange-brown or pale cream to cream, Powder or crystalline powder or crystals or flakes

Molecular weight: 185.95

Ref: 02-A12410

Iodoacetic acid

CAS: 64-69-7

Iodoacetic acid

Formula: C₂H₃IO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 185.95g/mol

Ref: 54-OR322006

Iodoacetic acid

CAS: 64-69-7

Formula: ICH₂CO₂H

Purity: ≥ 97.0%

Color and Shape: White to yellow or brown powder or flakes

Molecular weight: 185.95

Ref: 7W-GK0863

Iodoacetic acid

Controlled Product

CAS: 64-69-7

Formula: C₂H₃IO₂

Color and Shape: Neat

Molecular weight: 185.95

Ref: 04-C14331900

Iodoacetic Acid

Controlled Product

CAS: 64-69-7

Applications Used as a general reagent in acylation reactions. A byproduct formed in treated waters, and found in marine life.
E0
References Zuckermann, R.N. et al.; J. Am. Chem. Soc., 115, 10646 (1992); Bull, R., et al.: Toxicol. Appl. Pharmacol., 182, 55 (2002), Mitch, W., et al.: Water Sci. Technol., 2, 191 (2002),

Formula: C₂H₃IO₂

Color and Shape: Amber

Molecular weight: 185.95

Ref: TR-I685520

Iodoacetic Acid 2-13C

Controlled Product

CAS: 64-69-7

Applications Iodoacetic Acid 2-13C is labelled Iodoacetic Acid (I685520) which is used as a general reagent in acylation reactions. It is also a byproduct formed in treated waters, and found in marine life.
References Zuckermann, R.N. et al.; J. Am. Chem. Soc., 115, 10646 (1992); Bull, R., et al.: Toxicol. Appl. Pharmacol., 182, 55 (2002); Mitch, W., et ;l.: Water Sci. Technol., 2, 191 (2002)

Formula: CCH₃IO₂

Color and Shape: Neat

Molecular weight: 186.941

Ref: TR-I685522

Iodoaceticacid

CAS: 64-69-7

Iodoacetic acid is a non-steroidal anti-inflammatory drug that is used to relieve pain and reduce inflammation. It reduces the production of prostaglandin E2, which is a chemical mediator of inflammation. Iodoacetic acid has been shown to have no significant effects on energy metabolism or response element activity in human polymorphonuclear leukocytes. Iodoacetic acid has shown to be an effective inhibitor of the enzyme form that converts dinucleotide phosphate (NAD) into NADH (NADase). This compound is stable in sephadex g-100, which allows for easy separation by high-performance liquid chromatography (HPLC). The analytical method for iodoacetic acid involves adding the compound to a buffer solution containing sephadex g-100 and measuring the decrease in light transmission at 236 nm over time.

Formula: C₂H₃IO₂

Purity: Min. 95%

Molecular weight: 185.95 g/mol

Ref: 3D-AAA06469