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CAS 64-75-5

:

(-)-Tetracycline hydrochloride

Description:
(-)-Tetracycline hydrochloride is a broad-spectrum antibiotic belonging to the tetracycline class, primarily used to treat various bacterial infections. It is characterized by its complex polycyclic structure, which includes four fused rings, contributing to its ability to inhibit protein synthesis in bacteria by binding to the 30S ribosomal subunit. This compound is typically presented as a hydrochloride salt, enhancing its solubility in water. (-)-Tetracycline hydrochloride exhibits a yellow to orange color and is sensitive to light, which can lead to degradation. It is effective against a wide range of gram-positive and gram-negative bacteria, as well as some protozoa. The substance is also known for its anti-inflammatory properties and is sometimes used in the treatment of acne and other skin conditions. However, its use can lead to side effects, including gastrointestinal disturbances and photosensitivity. Due to its potential to cause tooth discoloration in children, its use is generally avoided in pregnant women and young children. Proper storage away from light and moisture is essential to maintain its stability and efficacy.
Formula:C22H24N2O8·ClH
InChI:InChI=1S/C22H24N2O8.ClH/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28;/h4-6,9-10,15,25,27-28,31-32H,7H2,1-3H3,(H2,23,30);1H/t9-,10-,15-,21+,22-;/m0./s1
InChI key:InChIKey=XMEVHPAGJVLHIG-FMZCEJRJSA-N
SMILES:O[C@@]12[C@@](C[C@]3(C(=C1O)C(=O)C=4C([C@@]3(C)O)=CC=CC4O)[H])([C@H](N(C)C)C(O)=C(C(N)=O)C2=O)[H].Cl
Synonyms:
  • (2E,6S,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione hydrochloride
  • (2Z,4S,4aS,5aS,6S,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione hydrochloride
  • 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride (1:1), (4S,4aS,5aS,6S,12aS)-
  • 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride
  • 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, (4S,4aS,5aS,6S,12aS)-
  • 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, [4S-(4α,4aα,5aα,6β,12aα)]-
  • 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthalenecarboxamide hydrochloride
  • 4-(Dimethylamino)-3,6,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-1,4,4A,5,5A,6,11,12A-Octahydrotetracene-2-Carboxamide Hydrochloride (1:1)
  • Achro
  • Achromycin hydrochloride
  • See more synonyms
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products per page.Found 28 products.
  • Tetracycline Hydrochloride

    CAS:
    Formula:C22H24N2O8HCl
    Molecular weight:444.4 : 36.46

    Ref: ST-EA-CP-T200003

    10mg
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    25mg
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    50mg
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    100mg
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  • Tetracycline hydrochloride

    CAS:
    <p>Antibiotic of tetracycline class; protein synthesis inhibitor</p>
    Formula:C22H25ClN2O8
    Color and Shape:Yellow Powder
    Molecular weight:480.9 g/mol

    Ref: 3D-AT28073

    1kg
    490.00€
    2kg
    770.00€
    5kg
    1,227.00€
    10kg
    2,182.00€
    500g
    322.00€
  • Tetracycline hydrochloride - USP

    CAS:
    <p>Tetracycline hydrochloride - USP is a broad-spectrum antibiotic, which is a synthetic derivative of chlortetracycline produced from the bacterium *Streptomyces aureofaciens*. It functions by inhibiting protein synthesis in bacteria, specifically binding to the 30S ribosomal subunit. This action prevents the attachment of aminoacyl-tRNA to the mRNA-ribosome complex, thereby halting bacterial growth and replication.</p>
    Formula:C22H25ClN2O8
    Color and Shape:Yellow Powder
    Molecular weight:480.9 g/mol

    Ref: 3D-AT168330

    1kg
    1,110.00€
    2kg
    1,480.00€
    5kg
    1,850.00€
    250g
    443.00€
    500g
    725.00€
  • Tetracycline Hydrochloride (TC) for tissue culture, 95%

    CAS:
    Formula:C22H24N2O8·HCl
    Purity:min. 95%
    Color and Shape:Yellow, Crystalline powder
    Molecular weight:480.90

    Ref: SR-82175

    5g
    25.00€
    25g
    54.00€
    100g
    135.00€
  • Tetracycline Hydrochloride (TC), 95%

    CAS:
    Formula:C22H24N2O8·HCl
    Purity:min. 95%
    Color and Shape:Yellow, Crystalline powder
    Molecular weight:480.90

    Ref: SR-38614

    5g
    28.00€
    25g
    35.00€
    100g
    97.00€
  • Tetracycline hydrochloride

    CAS:
    Purity:98%
    Molecular weight:479.89

    Ref: 10-F951532

    5g
    14.00€
    25g
    20.00€
  • Tetracycline hydrochloride, Antibiotic for Culture Media Use Only

    CAS:
    <p>Tetracycline hydrochloride is a broad-spectrum antibiotic and is an electron transfer agent. It has been shown to be effective against bacterial infections in humans and has been used in cultures for the prevention of bacterial contamination. As an electron transfer agent, it is used in electron microscopy to study the surface of biological cells. Tetracycline hydrochloride enters bacterial cells by diffusion and interacts with the cytoplasmic membrane, where it induces a redox reaction that leads to cell death. The efficacy of tetracycline hydrochloride in treating candida albicans (yeast) was studied using in-vitro activity and showed that carboxymethyl chitosan nanoparticles were able to enhance the treatment efficiency.</p>
    Formula:C22H25ClN2O8
    Purity:Min. 88.0 Area-%
    Molecular weight:480.90 g/mol

    Ref: 3D-T-1961

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  • Tetracycline hydrochloride (10mg/ml)

    CAS:
    <p>Tetracycline hydrochloride (10mg/ml)</p>
    Color and Shape:Solution
    Molecular weight:494.92g/mol

    Ref: 54-BIG1033

    10ml
    Discontinued
    25ml
    Discontinued
    100ml
    Discontinued
    Discontinued product