CAS 64-85-7

Deoxycorticosterone

Description:

Deoxycorticosterone (DOC) is a steroid hormone that plays a crucial role in the regulation of electrolyte and water balance in the body. It is classified as a mineralocorticoid and is produced in the adrenal cortex. DOC is characterized by its structure, which includes a cyclopentanoperhydrophenanthrene core typical of steroid compounds, with specific functional groups that influence its biological activity. It is less potent than aldosterone, another mineralocorticoid, but still contributes to sodium retention and potassium excretion. DOC is involved in the renin-angiotensin-aldosterone system, impacting blood pressure regulation. In terms of physical properties, it is a white to off-white crystalline powder that is soluble in organic solvents but has limited solubility in water. Its biological effects are mediated through mineralocorticoid receptors, influencing gene expression and cellular function. Due to its role in the endocrine system, abnormalities in DOC levels can be associated with various health conditions, including adrenal insufficiency and hypertension.

Formula: C₂₁H₃₀O₃

InChI: InChI=1S/C21H30O3/c1-20-9-7-14(23)11-13(20)3-4-15-16-5-6-18(19(24)12-22)21(16,2)10-8-17(15)20/h11,15-18,22H,3-10,12H2,1-2H3/t15-,16-,17-,18+,20-,21-/m0/s1

InChI key: InChIKey=ZESRJSPZRDMNHY-YFWFAHHUSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(CC3)=CC(=O)CC4)(CC1)[H])[H])(CC[C@@H]2C(CO)=O)[H]

Synonyms:

• 11-Dehydroxycorticosterone
• 11-Deoxycorticosterone
• 11-Desoxycorticosterone
• 21-Hydroxy-3,20-dioxopregn-4-ene
• 21-Hydroxy-Δ4-pregnane-3,20-dione
• 21-Hydroxy-Δ4-pregnene-3,20-dione
• 21-Hydroxy-Δ⁴-pregnane-3,20-dione
• 21-Hydroxy-Δ⁴-pregnene-3,20-dione
• 21-Hydroxypregn-4-Ene-3,20-Dione
• 21-Hydroxyprogesterone
• 4-Pregnen-21-ol-3,20-dione
• Cortexone
• Corticosterone, 11-deoxy-
• DOC
• DOC (steroid)
• Deoxycorticosterone
• Deoxycorticosterone Crystalline
• Deoxycortone
• Desoxicortona
• Desoxycorton
• Desoxycortone
• Kendall's desoxy compound B
• Nsc 11319
• Pregn-4-ene-3,20-dione, 21-hydroxy-
• Reichstein's substance Q
• Δ4-Pregnene-21-ol-3,20-dione

21-Hydroxyprogesterone

CAS: 64-85-7

Formula: C₂₁H₃₀O₃

Purity: >95.0%(HPLC)(qNMR)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 330.47

Ref: 3B-D6119

11-DeoXycorticosterone

CAS: 64-85-7

Formula: C₂₁H₃₀O₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 330.4611

Ref: IN-DA003DUV

21-Hydroxyprogesterone

CAS: 64-85-7

Formula: C₂₁H₃₀O₃

Purity: ≥ 97.0%

Color and Shape: White to light-yellow powder or crystals

Molecular weight: 330.46

Ref: 7W-GL4964

Deoxycorticosterone

CAS: 64-85-7

Deoxycorticosterone

Purity: ≥95%

Molecular weight: 330.46g/mol

Ref: 54-BUP16353

21-Hydroxyprogesterone

Controlled Product

CAS: 64-85-7

Formula: C₂₁H₃₀O₃

Color and Shape: Neat

Molecular weight: 330.46

Ref: 04-C14241050

11-Deoxy Corticosterone

CAS: 64-85-7

Formula: C₂₁H₃₀O₃

Molecular weight: 330.47

Ref: 4Z-C-10410

11-Deoxy Corticosterone

Controlled Product

CAS: 64-85-7

Applications A mineralocorticoid that occurs in adrenal cortex. It acts as a precursor to Aldosterone (A514700).
References Bohl, C., et al.: J. Med.Chem., 47, 3765 (2004), Smith, J., et al.: Steroids, 73, 1160 (2008),

Formula: C₂₁H₃₀O₃

Color and Shape: White To Light Yellow

Molecular weight: 330.46

Ref: TR-D232590

11-Deoxy Corticosterone-d7

Controlled Product

CAS: 64-85-7

Applications Labelled Deoxycorticosterone. A mineralocorticoid that occurs in adrenal cortex. It acts as a precursor to Aldosterone (A514700).
References Bohl, C., et al.: J. Med.Chem., 47, 3765 (2004), Smith, J., et al.: Steroids, 73, 1160 (2008),

Formula: C₂₁H₂₃D₇O₃

Color and Shape: White To Off-White

Molecular weight: 337.5

Ref: TR-D232593

11-Deoxycorticosterone

Controlled Product

CAS: 64-85-7

11-Deoxycorticosterone is a mineralocorticoid that binds to the P2Y receptor. It has been shown that 11-deoxycorticosterone has no effect on blood pressure in low doses, but when given at high doses it can cause hypertension. The drug also causes some cardiac effects, such as increased heart rate and contraction force. 11-Deoxycorticosterone is metabolized by deoxycorticosterone acetate into carbenoxolone sodium and then excreted in the urine.

Formula: C₂₁H₃₀O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 330.46 g/mol

Ref: 3D-FD21043

11-DeoXycorticosterone

CAS: 64-85-7

Purity: 97%

Molecular weight: 330.4679871

Ref: 10-F866023

Deoxycorticosterone

CAS: 64-85-7

Deoxycorticosterone, an adrenal steroid, is an aldosterone precursor with mineralocorticoid effects.

Formula: C₂₁H₃₀O₃

Purity: 98.19%

Color and Shape: Solid

Molecular weight: 330.46

Ref: TM-T20302

11-Deoxy Corticosterone

CAS: 64-85-7

Formula: C₂₁H₃₀O₃

Molecular weight: 330.46

Ref: ST-EA-CP-A321010