CAS 640-60-8

Phenyl tosylate

Description:

Phenyl tosylate, with the CAS number 640-60-8, is an organic compound that serves as an important reagent in organic synthesis. It is characterized by the presence of a phenyl group attached to a tosylate moiety, which is derived from p-toluenesulfonic acid. This compound typically appears as a colorless to pale yellow liquid and is known for its stability under standard conditions. Phenyl tosylate is primarily utilized as a leaving group in nucleophilic substitution reactions, making it valuable in the synthesis of various organic compounds. Its reactivity is attributed to the tosylate group, which enhances the electrophilicity of the phenyl ring, facilitating the displacement by nucleophiles. Additionally, phenyl tosylate is soluble in organic solvents, such as dichloromethane and ether, but has limited solubility in water. Safety considerations include handling it with care, as it can be irritating to the skin and eyes. Overall, phenyl tosylate is a versatile compound in synthetic organic chemistry, contributing to the formation of more complex molecular structures.

Formula: C₁₃H₁₂O₃S

InChI: InChI=1S/C13H12O3S/c1-11-7-9-13(10-8-11)17(14,15)16-12-5-3-2-4-6-12/h2-10H,1H3

InChI key: InChIKey=KZQFPRKQBWRRHQ-UHFFFAOYSA-N

SMILES: S(OC1=CC=CC=C1)(=O)(=O)C2=CC=C(C)C=C2

Synonyms:

• 2-[[(4-Methylphenyl)sulfonyl]oxy]benzene
• Benzenesulfonic acid, 4-methyl-, phenyl ester
• NSC 10407
• NSC 14917
• Phenyl 4-Methylbenzenesulfonate
• Phenyl 4-toluenesulfonate
• Phenyl p-methylbenzenesulfonate
• Phenyl p-toluenesulfonate
• Phenyl toluenesulfonate
• Phenyl tosylate
• Phenyltosylate

Phenyl p-Toluenesulfonate

CAS: 640-60-8

Formula: C₁₃H₁₂O₃S

Purity: >99.0%(GC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 248.30

Ref: 3B-P0239

Phenyl 4-methylbenzenesulfonate

CAS: 640-60-8

Formula: C₁₃H₁₂O₃S

Purity: 99%

Color and Shape: Solid

Molecular weight: 248.2976

Ref: IN-DA003U13

Phenyl P-Toluenesulfonate

CAS: 640-60-8

Phenyl P-Toluenesulfonate

Purity: 99%

Molecular weight: 248.30g/mol

Ref: 54-OR1014643

Phenyl tosylate

CAS: 640-60-8

Formula: C₁₃H₁₂O₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 248.3

Ref: 10-F043485

Phenyl Tosylate

Controlled Product

CAS: 640-60-8

Applications Phenyl Tosylate is an intermediate in synthesizing Diclofenac-13C6 Sodium Salt (D436453), which is a labelled analogue of Diclofenac Sodium Salt (D436450).
References Kenny, J. R., et al.: J. Med. Chem., 47, 2816 (2004), Sasaki, A., et al.: J. Pharmacol. Sci., 108, 266 (2008); Dalvie, D., et al.: Chem. Res. Toxicol., 22, 357 (2009)

Formula: C₁₃H₁₂O₃S

Color and Shape: Neat

Molecular weight: 248.298

Ref: TR-P338280