CAS 640-87-9

21-(Acetyloxy)-17-hydroxypregn-4-ene-3,20-dione

Description:

The chemical substance known as 21-(Acetyloxy)-17-hydroxypregn-4-ene-3,20-dione, with the CAS number 640-87-9, is a synthetic derivative of the steroid hormone progesterone. It is characterized by the presence of an acetoxy group at the 21 position and a hydroxyl group at the 17 position, which contribute to its biological activity. This compound is often utilized in pharmaceutical applications, particularly in hormone replacement therapies and contraceptives, due to its progestational effects. It exhibits a steroidal structure, which is typical for compounds in this class, and is soluble in organic solvents. The presence of the acetoxy group enhances its lipophilicity, influencing its absorption and distribution in biological systems. Additionally, this compound may undergo metabolic transformations in the body, impacting its pharmacokinetics and efficacy. Overall, 21-(Acetyloxy)-17-hydroxypregn-4-ene-3,20-dione plays a significant role in reproductive health and is a subject of interest in medicinal chemistry.

Formula: C₂₃H₃₂O₅

InChI: InChI=1S/C23H32O5/c1-14(24)28-13-20(26)23(27)11-8-19-17-5-4-15-12-16(25)6-9-21(15,2)18(17)7-10-22(19,23)3/h12,17-19,27H,4-11,13H2,1-3H3/t17-,18+,19+,21+,22+,23+/m1/s1

InChI key: InChIKey=HPAKILCZTKWIFK-JZTHCNPZSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(CC3)=CC(=O)CC4)(CC1)[H])[H])(CC[C@@]2(C(COC(C)=O)=O)O)[H]

Synonyms:

• 11-Deoxycortisol 21-acetate
• 17,21-Dihydroxypregn-4-ene-3,20-dione 21-acetate
• 17-Alpha,21-Dihydroxypregn-4-Ene-3,20-Dione 21-Acetate
• 17-Hydroxy-21-acetoxyprogesterone
• 17-Hydroxy-3,20-Dioxopregn-4-En-21-Yl Acetate
• 17α-Hydroxy-11-deoxycorticosterone-21-acetate
• 21-(Acetyloxy)-17-hydroxypregn-4-ene-3,20-dione
• 21-Acetoxy-17-hydroxypregn-4-ene-3,20-dione
• 21-Acetoxy-17α-hydroxyprogesterone
• 4-Pregnene-17α,21-diol-3,20-dione 21-acetate
• Cortexolone 21-acetate
• Corticosterone,11-deoxy-17-hydroxy-, 21-acetate
• Cortodoxon 21-acetate
• NSC 81196
• Pregn-4-ene-3,20-dione, 21-(acetyloxy)-17-hydroxy-
• Pregn-4-ene-3,20-dione,17,21-dihydroxy-, 21-acetate
• RSA
• Reichstein substance S 21-acetate
• Reichstein's substance S acetate

21-(Acetyloxy)-17-hydroxypregn-4-ene-3,20-dione

CAS: 640-87-9

Formula: C₂₃H₃₂O₅

Purity: >97.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 388.50

Ref: 3B-A3212

Cortexolone 21-Acetate (17-Hydroxy-3,20-dioxopregn-4-en-21-yl acetate)

CAS: 640-87-9

Esters of acetic acid, nesoi

Formula: C₂₃H₃₂O₅

Color and Shape: White Powder

Molecular weight: 388.22497

Ref: 45-1A11670

21-(Acetyloxy)-17-Hydroxypregn-4-Ene-3,20-Dione

CAS: 640-87-9

Formula: C₂₃H₃₂O₅

Purity: 99%

Color and Shape: Solid

Molecular weight: 388.4972

Ref: IN-DA00JNTF

Hydrocortisone EP Impurity K

CAS: 640-87-9

Formula: C₂₃H₃₂O₅

Molecular weight: 388.51

Ref: 4Z-H-103023

21-(Acetyloxy)-17-Hydroxypregn-4-Ene-3,20-Dione

CAS: 640-87-9

21-(Acetyloxy)-17-Hydroxypregn-4-Ene-3,20-Dione

Purity: 99%

Molecular weight: 388.5g/mol

Ref: 54-OR1028743

17-Hydroxy-3,20-dioxopregn-4-en-21-yl Acetate (Reichstein's Substance S 21-Acetate)

CAS: 640-87-9

Color and Shape: Neat

Ref: 86-MM0185.27

17a-Hydroxy-11-deoxycorticosterone-21-acetate

Controlled Product

CAS: 640-87-9

Impurity Hydrocortisone EP Impurity K
Applications 17α-Hydroxy-11-deoxycorticosterone-21-acetate (Hydrocortisone EP Impurity K) is an acetate substance 'S' - a synthetic steroid as carbaryl synergist.
References Brown-Grant, K., et al.: J. Endocrinol., 38, 145 (1967), Brzezowska, E., et al.: J. Steroid Molec. Biol., 57, 357 (1996), Kamihira, M., et al.: Agric. Biol. Chem., 51, 407 (1987), Fabre, C., et al.: Biotechnol. Bioeng., 64, 392 (1999),

Formula: C₂₃H₃₂O₅

Color and Shape: White

Molecular weight: 388.4972

Ref: TR-H934800

11-Deoxy-17-hydrocorticosterone 21-acetate

Controlled Product

CAS: 640-87-9

11-Deoxy-17-hydrocorticosterone 21-acetate is a steroid hormone that is produced in the zona fasciculata of the adrenal cortex. It has been shown to have immunoactive effects and can be used to treat inflammatory conditions such as colitis. 11-Deoxy-17-hydrocorticosterone 21-acetate has also been shown to have antiinflammatory properties, which may be due to its inhibition of cytokine production. The drug is metabolized by cytochrome P450 enzymes, including CYP3A4 and CYP2C8, and bovine serum albumin. This drug also binds to serum albumin, which prevents it from being eliminated from the body, prolonging its half life in the bloodstream.

Formula: C₂₃H₃₂O₅

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 388.5 g/mol

Ref: 3D-FD67118

Cortexolone 21-acetate

CAS: 640-87-9

Formula: C₂₃H₃₂O₅

Molecular weight: 388.5

Ref: ST-EA-CP-C158002