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CAS 64003-50-5

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20-Deoxysalinomycin

Description:
20-Deoxysalinomycin is a polyether antibiotic that belongs to the salinomycin family, which is primarily known for its ionophoric properties. This compound is characterized by its ability to transport monovalent cations, such as sodium and potassium, across biological membranes, which can disrupt cellular ion homeostasis. It exhibits potent antimicrobial activity, particularly against certain strains of bacteria and fungi, and has garnered interest for its potential applications in agriculture and medicine, particularly in cancer treatment due to its selective toxicity towards cancer stem cells. The molecular structure of 20-Deoxysalinomycin includes a complex polycyclic framework, contributing to its biological activity. Additionally, it is known for its relatively low solubility in water, which can affect its bioavailability and efficacy in various applications. As with many polyether antibiotics, safety and toxicity profiles are critical considerations in its use, necessitating further research to fully understand its mechanisms and potential therapeutic benefits.
Formula:C42H70O10
InChI:InChI=1/C42H70O10/c1-11-30(38(45)46)32-16-15-24(4)36(49-32)28(8)34(43)27(7)35(44)31(12-2)37-25(5)23-26(6)42(50-37)19-14-18-41(52-42)22-21-39(10,51-41)33-17-20-40(47,13-3)29(9)48-33/h14,19,24-34,36-37,43,47H,11-13,15-18,20-23H2,1-10H3,(H,45,46)
Synonyms:
  • SY-1
  • Antibiotic SY-1
  • 20-Deoxysalinomycin
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