CAS 64014-06-8

Acetaminophen-cysteine

Description:

Acetaminophen-cysteine, with the CAS number 64014-06-8, is a conjugate formed from the reaction of acetaminophen (paracetamol) and cysteine, an amino acid. This compound is primarily studied in the context of drug metabolism and detoxification processes. It exhibits characteristics typical of both acetaminophen and cysteine, including potential antioxidant properties due to the presence of the thiol group from cysteine. The compound is soluble in water, which facilitates its biological interactions. Acetaminophen-cysteine is of interest in pharmacology, particularly regarding its role in mitigating the hepatotoxic effects of acetaminophen overdose, as it may help in the detoxification of reactive metabolites. Additionally, it may serve as a biomarker for acetaminophen exposure and toxicity. The stability and reactivity of this compound can be influenced by pH and temperature, making it important to consider these factors in experimental settings. Overall, acetaminophen-cysteine represents a significant area of research in understanding drug interactions and metabolic pathways.

Formula: C₁₁H₁₄N₂O₃S

InChI: InChI=1S/C11H14N2O3S/c1-7(14)13-8-2-4-9(5-3-8)17-6-10(12)11(15)16/h2-5,10H,6,12H2,1H3,(H,13,14)(H,15,16)/t10-/m0/s1

InChI key: InChIKey=ZOZXXYPCOKGXOE-JTQLQIEISA-N

SMILES: S(C[C@@H](C(O)=O)N)C1=CC=C(NC(C)=O)C=C1

Synonyms:

• Acetaminophen-cysteine
• S-[4-(Acetylamino)phenyl]-L-cysteine
• L-Cysteine, S-[4-(acetylamino)phenyl]-

Acetaminophen-cysteine

Controlled Product

CAS: 64014-06-8

Formula: C₁₁H₁₄N₂O₃S

Color and Shape: Neat

Molecular weight: 254.31

Ref: TR-A161255

Acetaminophen cysteine

CAS: 64014-06-8

Acetaminophen cysteine is a prodrug of acetaminophen that is metabolized by the liver into acetaminophen. Acetaminophen cysteine has been shown to be safe and effective in children with fever-associated pain and as an analgesic for acute pain management in adults. It has a good safety profile, with minimal toxicity observed at therapeutic doses. Acetaminophen cysteine may be useful for patients who are unable to take or do not respond to standard doses of acetaminophen due to intolerance or lack of response. The pharmacokinetics of acetaminophen cysteine have been studied in healthy volunteers, as well as in patients with chronic renal failure and hepatic impairment. Pharmacokinetic data suggest that acetaminophen cysteine is well tolerated and can be used as an alternative treatment for patients who are unable to take or do not respond to standard doses of acetaminophen.

Formula: C₁₁H₁₄N₂O₃S

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 254.31 g/mol

Ref: 3D-FA165558