CAS 64019-93-8

Dipivefrin hydrochloride

Description:

Dipivefrin hydrochloride is a synthetic prodrug of epinephrine, primarily used in ophthalmology for the treatment of glaucoma and ocular hypertension. It is characterized by its ability to penetrate the cornea more effectively than epinephrine itself due to its lipophilic nature, which enhances its therapeutic efficacy. The compound is typically presented as a white to off-white crystalline powder and is soluble in water, making it suitable for formulation in eye drops. Dipivefrin acts as an adrenergic agonist, stimulating alpha and beta-adrenergic receptors, which leads to increased aqueous humor outflow and decreased intraocular pressure. Its pharmacokinetics involve conversion to epinephrine in the eye, providing a localized effect with reduced systemic side effects. The hydrochloride salt form enhances its stability and solubility. As with any medication, potential side effects may include ocular irritation or systemic effects due to adrenergic stimulation, necessitating careful monitoring during use. Overall, dipivefrin hydrochloride is an important therapeutic agent in managing certain eye conditions.

Formula: C₁₉H₂₉NO₅·ClH

InChI: InChI=1S/C19H29NO5.ClH/c1-18(2,3)16(22)24-14-9-8-12(13(21)11-20-7)10-15(14)25-17(23)19(4,5)6;/h8-10,13,20-21H,11H2,1-7H3;1H

InChI key: InChIKey=VKFAUCPBMAGVRG-UHFFFAOYSA-N

SMILES: O(C(C(C)(C)C)=O)C1=C(OC(C(C)(C)C)=O)C=CC(C(CNC)O)=C1.Cl

Synonyms:

• 4-[1-Hydroxy-2-(Methylamino)Ethyl]Benzene-1,2-Diyl Bis(2,2-Dimethylpropanoate) Hydrochloride (1:1)
• D Epifrin
• Diopine
• Diphemin
• Dipivefrine HCL
• Dipivefrine hydrochloride
• Pivalephrine
• Propanoic acid, 2,2-dimethyl-, 1,1′-[4-[1-hydroxy-2-(methylamino)ethyl]-1,2-phenylene] ester, hydrochloride (1:1)
• Propanoic acid, 2,2-dimethyl-, 4-[1-hydroxy-2-(methylamino)ethyl]-1,2-phenylene ester, hydrochloride
• Propine
• Dipivefrin hydrochloride

DIPIVEFRINE FOR SYSTEM SUITABILITY CRS

CAS: 64019-93-8

DIPIVEFRINE FOR SYSTEM SUITABILITY CRS

Formula: C₁₉H₃₀ClNO₅

Molecular weight: 387.8982

Ref: 41-Y0000394

DIPIVEFRINE HYDROCHLORIDE CRS

CAS: 64019-93-8

DIPIVEFRINE HYDROCHLORIDE CRS

Formula: C₁₉H₃₀ClNO₅

Color and Shape: Crystalline Powder. White. Whitish. Powder.

Molecular weight: 387.8982

Ref: 41-Y0000376

Dipivefrine hydrochloride

CAS: 64019-93-8

Dipivefrine hydrochloride

Formula: C₁₉H₂₉NO₅HCl

Purity: 99.4%

Color and Shape: White To Off-White

Molecular weight: 387.18125

Ref: 47-673

Dipivefrin hydrochloride

CAS: 64019-93-8

Dipivefrin hydrochloride (Dipivefrin HCl) that is available as an ophthalmic solution is a prodrug of adrenaline, which is used to treat glaucoma.

Formula: C₁₉H₂₇NO₅·HCl

Purity: 99.22% - 99.92%

Color and Shape: Less Gas With A Sweet Odor Colorless Gas With A Sweet Odor

Molecular weight: 387.9

Ref: TM-T0103

Dipivefrine-d6 HCl

CAS: 52365-63-6, 64019-93-8

Formula: C₁₉H₂₃D₆NO₅·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 357.48 36.46

Ref: 4Z-D-195003

Dipivefrine HCl

CAS: 64019-93-8

Formula: C₁₉H₂₉NO₅·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 351.45 36.46

Ref: 4Z-D-195001

Dipivefrin hydrochloride

CAS: 64019-93-8

Dipivefrin hydrochloride

Purity: ≥98%

Molecular weight: 387.9g/mol

Ref: 54-BUP11941

Dipivefrine Hydrochloride

Controlled Product

CAS: 64019-93-8

Formula: C₁₉H₂₉NO₅·ClH

Color and Shape: Neat

Molecular weight: 387.90

Ref: TR-D492155

Dipivefrine-D₃- Hydrochloride

Controlled Product

CAS: 64019-93-8

Formula: C₁₉D₃H₂₆NO₅·HCl

Color and Shape: Neat

Molecular weight: 390.917

Ref: TR-D434661

Dipivefrin hydrochloride

CAS: 64019-93-8

Dipivefrin hydrochloride is a drug that belongs to the class of prostaglandin analogues. It is used as a topical ophthalmic solution for the treatment of glaucoma and other intraocular disorders. Dipivefrin hydrochloride is not active against microbial infection or choroidal neovascularization, but has been shown to be effective in the pharmacological treatment of metabolic disorders. This drug interacts with the prostaglandin receptors in the eye, which can lead to increased production of cyclic GMP (cGMP), a second messenger that causes relaxation of smooth muscles in blood vessels and leads to decreased intraocular pressure. Dipivefrin hydrochloride also has antimicrobial properties due to its ability to inhibit bacterial growth through binding with microbial cell membranes, thereby inhibiting protein synthesis.

Formula: C₁₉H₃₀ClNO₅

Purity: Min. 95%

Molecular weight: 387.9 g/mol

Ref: 3D-FD152268

Dipivefrin Hydrochloride

CAS: 64019-93-8

Aromatic amino-alcohol-phenols, aromatic amino-acid-phenols and other aromatic amino compounds with oxygen function

Formula: C₁₉H₂₉NO₅·ClH

Color and Shape: Powder

Molecular weight: 387.18125

Ref: 45-1220302

Dipivefrine impurity standard

CAS: 64019-93-8

Dipivefrine impurity standard

Color and Shape: White To Off-White

Ref: 47-659