CAS 640279-88-5

Azelastine Related Compound F (4-[4-(4-Chlorobenzyl)-1-oxophthalazin-2(1H)-yl]-1-methylazepane 1-oxide)

CAS: 640279-88-5

Heterocyclic compounds with nitrogen hetero-atom(s) only, aromatic or modified aromatic, nesoi

Formula: C₂₂H₂₄ClN₃O₂

Color and Shape: White Solid

Molecular weight: 397.1557

Ref: 45-1046213

Azelastine USP Related Compound F (Azelastine N-Oxide) (Mixture of Diastereomers)

CAS: 640279-88-5

Formula: C₂₂H₂₄ClN₃O₂

Color and Shape: White To Off-White Solid

Molecular weight: 397.90

Ref: 4Z-A-6813

Azelastine N-Oxide (Mixture of Diastereomers)

Controlled Product

CAS: 640279-88-5

Stability Hygroscopic
Applications A metabolite of Azelastine (A808250).
References Heinemann, U. et al.: J. Chrom. B Anal. Tech. Biomed. Life Sci., 793, 389 (2003); Tasaka, K., et al.: Arzneim.-Forsch., 29, 488 (1979);

Formula: C₂₂H₂₄ClN₃O₂

Color and Shape: Neat

Molecular weight: 397.90

Ref: TR-A808260

Azelastine N-oxide, mixture of diastereomers

CAS: 640279-88-5

Azelastine N-oxide is a racemic form of azelastine, an antihistamine. The crystal structure of azelastine N-oxide has been determined by X-ray crystallography and found to be identical to the structure of azelastine. Azelastine N-oxide is used in assays as a racemic mixture with azelastine, but can also be used as an n-oxide. Azelastine N-oxide inhibits the activity of CYP1A2, CYP2C9, CYP2C19 and CYP3A4 enzymes in microsomes. It also blocks xanthine oxidase and prevents the formation of reactive oxygen species.

Formula: C₂₂H₂₄ClN₃O₂

Purity: Min. 95%

Molecular weight: 397.9 g/mol

Ref: 3D-QAB27988