CAS 640281-90-9

Valopicitabine

Description:

Valopicitabine, with the CAS number 640281-90-9, is an antiviral compound that has been investigated primarily for its potential use in the treatment of hepatitis C virus (HCV) infections. It is a prodrug of the nucleoside analogue, which means it is converted into its active form within the body to exert its therapeutic effects. Valopicitabine functions by inhibiting viral replication, thereby reducing the viral load in infected individuals. The compound is characterized by its ability to interfere with the viral RNA synthesis, making it a crucial candidate in antiviral therapy. Its chemical structure includes specific functional groups that contribute to its activity and pharmacokinetics. Valopicitabine has undergone various clinical trials to assess its efficacy and safety profile, and while it shows promise, further research is necessary to fully establish its role in HCV treatment regimens. As with many antiviral agents, potential side effects and resistance development are important considerations in its therapeutic application.

Formula: C₁₅H₂₄N₄O₆

InChI: InChI=1S/C15H24N4O6/c1-7(2)10(17)12(21)25-11-8(6-20)24-13(15(11,3)23)19-5-4-9(16)18-14(19)22/h4-5,7-8,10-11,13,20,23H,6,17H2,1-3H3,(H2,16,18,22)/t8-,10+,11-,13-,15-/m1/s1

InChI key: InChIKey=TVRCRTJYMVTEFS-ICGCPXGVSA-N

SMILES: C[C@]1(O)[C@@H](O[C@H](CO)[C@H]1OC([C@H](C(C)C)N)=O)N2C(=O)N=C(N)C=C2

Synonyms:

• <span class="text-smallcaps">L</span>-Valine, 3′-ester with 2′-C-methylcytidine
• Nm-283
• Valopicitabine
• val-mCyd
• L-Valine, 3′-ester with 2′-C-methylcytidine

Valopicitabine

CAS: 640281-90-9

Valopicitabine is a prodrug that is converted to its active form, 3'-deoxy-3'-methylvalopicitabine, in the body. Valopicitabine inhibits viral replication by a mechanism that is not yet fully understood. It has been shown to inhibit NS3 protease and induce an interferon response. Valopicitabine has also been shown to inhibit Toll-like receptor 4 (TLR4) activity and elicit an antiviral response. Valopicitabine has low bioavailability, which may be due to its high lipophilicity.

Formula: C₁₅H₂₄N₄O₆

Purity: Min. 95%

Molecular weight: 356.37 g/mol

Ref: 3D-NV35082

Valopicitabine

CAS: 640281-90-9

Valopicitabine is an effective prodrug of the effective anti-HCV drug 2'-C-methylcytidine and can be used as a promising antiviral drug for the study of chronic

Formula: C₁₅H₂₄N₄O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 356.37

Ref: TM-T13281