CAS 6404-31-5

N-(Benzyloxycarbonyl)-D-proline

Description:

N-(Benzyloxycarbonyl)-D-proline, also known as Z-D-proline, is a derivative of the amino acid proline, characterized by the presence of a benzyloxycarbonyl (Z) protecting group. This compound is typically used in peptide synthesis as a protecting group for the amino functionality, enhancing the stability and reactivity of the proline residue during chemical reactions. It is a white to off-white crystalline solid, soluble in organic solvents such as methanol and dimethyl sulfoxide, but generally insoluble in water. The presence of the benzyloxycarbonyl group imparts increased lipophilicity, making it useful in various organic synthesis applications. N-(Benzyloxycarbonyl)-D-proline is also notable for its role in the synthesis of cyclic peptides and other complex organic molecules, where the proline structure contributes to the conformational rigidity and biological activity of the resulting compounds. As with many chemical substances, proper handling and storage are essential to maintain its stability and prevent degradation.

Formula: C₁₃H₁₅NO₄

InChI: InChI=1/C13H15NO4/c15-12(16)11-7-4-8-14(11)13(17)18-9-10-5-2-1-3-6-10/h1-3,5-6,11H,4,7-9H2,(H,15,16)/p-1/t11-/m1/s1

InChI key: InChIKey=JXGVXCZADZNAMJ-LLVKDONJSA-N

SMILES: C(OCC1=CC=CC=C1)(=O)N2[C@@H](C(O)=O)CCC2

Synonyms:

• (+)-Z-D-proline
• (2R)-1-(Benzyloxycarbonyl)pyrrolidine-2-carboxylic acid
• (2R)-1-Phenylmethoxycarbonylpyrrolidine-2-carboxylic acid
• (2R)-1-[(Benzyloxy)carbonyl]pyrrolidine-2-carboxylic acid
• (2R)-1-[(benzyloxy)carbonyl]pyrrolidine-2-carboxylate
• (Benzyloxycarbonyl)-<span class="text-smallcaps">D</span>-proline
• (R)-1-(Benzyloxycarbonyl)pyrrolidine-2-carboxylic acid
• (R)-N-BenzyloxycarbonyLproline
• 1,2-Pyrrolidinedicarboxylic acid, 1-(phenylmethyl) ester, (2R)-
• 1,2-Pyrrolidinedicarboxylic acid, 1-(phenylmethyl) ester, (R)-
• 1,2-Pyrrolidinedicarboxylic acid, 1-benzyl ester, <span class="text-smallcaps">D</span>-
• 1-(Benzyloxycarbonyl)-<span class="text-smallcaps">D</span>-proline
• <span class="text-smallcaps">D</span>-Cbz-Proline
• CBZ-D-Proline
• Cbz-D-Pro-OH
• N-(Benzyloxycarbonyl)-(R)-proline
• N-(Benzyloxycarbonyl)-<span class="text-smallcaps">D</span>-proline
• N-CBZ-D-Proline
• N-Carbobenzyloxy-<span class="text-smallcaps">D</span>-proline
• Z-D-Pro-OH
• N-(Benzyloxycarbonyl)-D-proline
• (Benzyloxycarbonyl)-D-proline
• 1,2-Pyrrolidinedicarboxylic acid, 1-benzyl ester, D-
• N-Z-D-PROLINE
• N-ALPHA-BENZYLOXYCARBONYL-D-PROLINE
• N-ALPHA-CARBOBENZOXY-D-PROLINE
• N-BENZYLOXYCARBONYLAMINO-D-PROLINE
• D-Z-PRO
• 1-[(BENZYLOXY)CARBONYL]PYRROLIDINE-2-CARBOXYLIC ACID
• N-ALPHA-CBZ-D-PROLINE
• N-CARBOBENZOXY-D-PROLINE
• N-ALPHA-CARBOBENZOXY-D-PYRROLIDINE-2-CARBOXYLIC ACID

N-Carbobenzoxy-D-proline

CAS: 6404-31-5

Formula: C₁₃H₁₅NO₄

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 249.27

Ref: 3B-C1730

Z-D-Pro-OH

CAS: 6404-31-5

Formula: C₁₃H₁₅NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 249.2625

Ref: IN-DA003BDG

(+)-Z-D-proline

CAS: 6404-31-5

Formula: C₁₃H₁₅NO₄

Molecular weight: 249.27

Ref: 7W-GM6538

(R)-1-(benzyloxycarbonyl)pyrrolidine-2-carboxylic acid

CAS: 6404-31-5

(R)-1-(benzyloxycarbonyl)pyrrolidine-2-carboxylic acid

Purity: 98%

Molecular weight: 249.26g/mol

Ref: 54-OR95426

(2R)-Pyrrolidine-2-carboxylic acid, N-CBZ protected

CAS: 6404-31-5

(2R)-Pyrrolidine-2-carboxylic acid, N-CBZ protected

Purity: 95%

Molecular weight: 249.26g/mol

Ref: 54-OR0767

Z-D-PRO-OH

CAS: 6404-31-5

Formula: C₁₃H₁₅NO₄

Molecular weight: 249.27

Ref: 4Z-P-166053

Z-D-Pro-OH

CAS: 6404-31-5

M03041 - Z-D-Pro-OH

Formula: C₁₃H₁₅NO₄

Purity: 98%

Color and Shape: Crystalline,Powder

Molecular weight: 249.266

Ref: 10-M03041

Z-D-Proline extrapure, 99%

CAS: 6404-31-5

Formula: C₁₃H₁₅NO₄

Purity: min. 99 %

Color and Shape: White to off white, Crystalline powder

Molecular weight: 249.3

Ref: SR-24037