CAS 641-36-1

Apocodeine

Description:

Apocodeine, with the CAS number 641-36-1, is an opiate derivative that is structurally related to codeine. It is characterized by its analgesic properties, which make it useful in pain management, although it is less potent than its parent compound, codeine. Apocodeine is typically classified as a weak opioid and may exhibit mild sedative effects. Its chemical structure includes a phenanthrene core, which is common among many opioids, and it possesses a hydroxyl group that contributes to its pharmacological activity. The substance is not widely used in clinical practice compared to other opioids, and its safety profile and potential for abuse are important considerations. As with other opioids, apocodeine can lead to dependence and withdrawal symptoms if used improperly. It is essential to handle apocodeine with caution, adhering to regulatory guidelines and considering its effects on the central nervous system. Overall, while apocodeine has potential therapeutic applications, its use must be carefully monitored to mitigate risks associated with opioid medications.

Formula: C₁₈H₁₉NO₂

InChI: InChI=1/C18H19NO2/c1-19-9-8-11-4-3-5-13-16(11)14(19)10-12-6-7-15(21-2)18(20)17(12)13/h3-7,14,20H,8-10H2,1-2H3/t14-/m1/s1

InChI key: InChIKey=DZUOQMBJJSBONO-CQSZACIVSA-N

SMILES: CN1[C@]2(C=3C(C=4C(C2)=CC=C(OC)C4O)=CC=CC3CC1)[H]

Synonyms:

• (-)-(R)-Apocodeine
• (-)-Apocodeine
• (6aR)-5,6,6a,7-Tetrahydro-10-methoxy-6-methyl-4H-dibenzo[de,g]quinolin-11-ol
• (R)-5,6,6a,7-Tetrahydro-10-methoxy-6-methyl-4H-dibenzo[de,g]quinolin-11-ol
• 4H-Dibenzo[de,g]quinolin-11-ol, 5,6,6a,7-tetrahydro-10-methoxy-6-methyl-, (R)-
• 4H-dibenzo[de,g]quinolin-11-ol, 5,6,6a,7-tetrahydro-10-methoxy-6-methyl-, (6aR)-
• 6aβ-Aporphin-11-ol, 10-methoxy-
• Apocodein

Apocodeine

CAS: 641-36-1

Formula: C₁₈H₁₉NO₂

Molecular weight: 281.36

Ref: 4Z-A-346001

R-(-)-Apocodeine

CAS: 641-36-1

Formula: C₁₈H₁₉NO₂

Ref: TR-TRC-A727100

R-(-)-Apocodeine

Controlled Product

CAS: 641-36-1

Applications A metabolite of Apomorphine (A727500). Dopamine receptor agonist. Emetic.
References Neumeyer, et al.: J. Med. Chem., 16, 1223 (1973), Fong, T., et al.: Cancer Res., 59, 99 (1999), Hayashi, Y., et al.: J. Biol. Chem., 278, 25166 (2003), O'Neill, J., et al.: Science, 320, 949 (2008),

Formula: C₁₈H₁₉NO₂

Color and Shape: Off White Solid

Molecular weight: 281.35

Ref: TR-A727100

R-(-)-Apocodeine (1.0mg/ml in Acetonitrile)

Controlled Product

CAS: 641-36-1

Formula: C₁₈H₁₉NO₂

Color and Shape: Single Solution

Molecular weight: 281.35

Ref: TR-KIT3050

Mixture of R-(-)-Apocodeine and (R)-Norapocodeine (2.5:1)

Controlled Product

CAS: 641-36-1

Formula: C₁₈H₁₉NO₂·C₁₇H₁₇NO₂

Color and Shape: Neat

Molecular weight: 548.67

Ref: TR-A727110