CAS 641-38-3

Alternariol

Description:

Alternariol is a mycotoxin produced by various species of the Alternaria fungus, commonly found in decaying plant material and certain food products. It is classified as a phenolic compound and is known for its potential toxicological effects, including mutagenicity and cytotoxicity. The molecular structure of alternariol features a hydroxyl group and a lactone ring, contributing to its chemical reactivity and biological activity. This compound is often studied for its implications in food safety, as it can contaminate crops such as tomatoes, fruits, and grains, posing health risks to consumers. In addition to its toxicological properties, alternariol has been investigated for its potential antioxidant activities, although its safety profile remains a concern. Regulatory agencies monitor its levels in food products to ensure consumer safety, and ongoing research aims to better understand its mechanisms of action and effects on human health. Overall, alternariol exemplifies the complex interplay between natural toxins and food safety.

Formula: C₁₄H₁₀O₅

InChI: InChI=1S/C14H10O5/c1-6-2-7(15)5-11-12(6)9-3-8(16)4-10(17)13(9)14(18)19-11/h2-5,15-17H,1H3

InChI key: InChIKey=CEBXXEKPIIDJHL-UHFFFAOYSA-N

SMILES: CC1=C2C=3C(C(=O)OC2=CC(O)=C1)=C(O)C=C(O)C3

Synonyms:

• 3,4,4'-Trihydroxy-6'-methyl-2-biphenylcarboxylic acid, gamma lactone
• 3,7,9-Trihydroxy-1-Methyl-Benzo[C]Chromen-6-One
• 3,7,9-Trihydroxy-1-methyl-6H-dibenzo[b,d]pyran-6-one
• 3,7,9-Trihydroxy-1-methylbenzo[c]chromen-6-one
• 6H-Dibenzo(b,d)pyran-6-one, 1-methyl-3,7,9-trihydroxy-
• 6H-Dibenzo[b,d]pyran-6-one, 3,7,9-trihydroxy-1-methyl-
• AOH
• Alternariol
• Brn 0244839
• Ccris 6734
• NSC 638263

Alternariol

CAS: 641-38-3

Alternariol

Formula: C₁₄H₁₀O₅

Purity: 99%

Color and Shape: off-white to slightly yellow powder

Molecular weight: 258.23g/mol

Ref: 54-BIA2301

Alternariol

CAS: 641-38-3

Formula: C₁₄H₁₀O₅

Purity: 95%~99%

Molecular weight: 258.229

Ref: BP-SBP03513

Alternariol

CAS: 641-38-3

Alternariol, a mycotoxin from Alternaria, has anti-HIV, anti-cancer properties and inhibits topoisomerases.

Formula: C₁₄H₁₀O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 258.23

Ref: TM-T14196

Alternariol

CAS: 641-38-3

Formula: C₁₄H₁₀O₅

Purity: ≥ 98.0%

Color and Shape: White to brown solid

Molecular weight: 258.23

Ref: 7W-GW2387

Alternariol

CAS: 641-38-3

Formula: C₁₄H₁₀O₅

Molecular weight: 258.23

Ref: 4Z-A-252001

Alternariol-d4

CAS: 641-38-3

Formula: C₁₄H₆D₄O₅

Color and Shape: White To Off-White Solid

Molecular weight: 262.25

Ref: 4Z-A-252002

Alternariol

CAS: 641-38-3

Alternariol is a natural product that is extracted from the plant Etoac. It has been shown to have anti-inflammatory properties in vitro and in vivo in murine hepatoma cells, as well as in human serum. Alternariol also has an effect on toll-like receptor signaling and pro-apoptotic protein expression. Alternariol was found to be inactive against methyl transferase enzymes, which can lead to its enzymatic inactivation. The LC-MS/MS method for the detection of alternariol was developed using a surface methodology.

Formula: C₁₄H₁₀O₅

Purity: Min. 95%

Color and Shape: Off-White To Beige To Light Brown Solid

Molecular weight: 258.23 g/mol

Ref: 3D-FA17330

Alternariol

CAS: 641-38-3

Formula: C₁₄H₁₀O₅

Molecular weight: 258.23

Ref: ST-EA-CP-A297000

Alternariol

CAS: 641-38-3

Stability Hygroscopic
Applications Alternariol is an alternaria mycotoxin and genotoxin, found in common edible crops. It inhibits the activity of various DNA-topoisomerases, increasing the rate of DNA strand breaks.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Asam S et al. J Agric Food Chem. 2009 Jun 24;57(12):5152-60.Fehr M et al. Mol Nutr Food Res. 2009 Apr;53(4):441-51Vejdovszky K. et al. Toxicol Lett. 2017 Feb 5;267:45-52.

Formula: C₁₄H₁₀O₅

Color and Shape: Light Brown

Molecular weight: 258.23

Ref: TR-A575760

Alternariol-d2

Controlled Product

CAS: 641-38-3

Applications Alternariol-d2 is labelled version of Alternariol (A575760), an alternaria mycotoxin and genotoxin found in common edible crops. It inhibits the activity of various DNA-topoisomerases, increasing the rate of DNA strand breaks.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Asam, S., et al.: J. Agric. Food Chem., 57, 5152 (2009); Fehr, M., et al.: Mol. Nut. Food Res., 53, 441 (2009); Tiemann, U., et al.: Toxicol. Lett., 186, 139 (2009)

Formula: C₁₄H₈D₂O₅

Color and Shape: Off-White To Dark Brown

Molecular weight: 260.24

Ref: TR-A575762