CAS 641-70-3

3-Nitrophthalic anhydride

Description:

3-Nitrophthalic anhydride is an organic compound characterized by its anhydride functional group and a nitro substituent on the phthalic structure. It is typically a yellow to brown solid at room temperature and is known for its reactivity, particularly in electrophilic aromatic substitution reactions due to the presence of the nitro group, which is a strong electron-withdrawing group. This compound is soluble in organic solvents such as acetone and chloroform but has limited solubility in water. It is primarily used in the synthesis of various chemical intermediates, including dyes, pharmaceuticals, and agrochemicals. Additionally, 3-nitrophthalic anhydride can undergo hydrolysis to form 3-nitrophthalic acid, which retains some of the properties of the anhydride. Safety precautions should be taken when handling this compound, as it may pose health risks, including irritation to the skin and respiratory system. Proper storage in a cool, dry place away from incompatible materials is essential to maintain its stability and prevent degradation.

Formula: C₈H₃NO₅

InChI: InChI=1/C8H3NO5/c10-7-4-2-1-3-5(9(12)13)6(4)8(11)14-7/h1-3H

InChI key: InChIKey=ROFZMKDROVBLNY-UHFFFAOYSA-N

SMILES: N(=O)(=O)C1=C2C(C(=O)OC2=O)=CC=C1

Synonyms:

• 1,3-Isobenzofurandione, 4-nitro-
• 1-Amino-2-Indolinon (CIS)
• 3 Nitro phthalic anyhydride
• 3-Nitrophthalic acid anhydride
• 4-Nitro-1,3-isobenzofurandione
• 4-Nitro-2-benzofuran-1,3-dione
• 4-Nitroisobenzofuran-1,3-dione
• NSC 27006
• NSC 4134
• Phthalic anhydride, 3-nitro-
• 3-Nitrophthalic anhydride
• 4-NITRO-ISOBENZOFURAN-1,3-DIONE
• 3-Isobenzofurandione,4-nitro-1
• 3-NITROPHTHALIC ANHYDRIDE ,99+%
• 4-Nitro-1,3-iso benzofurandione

3-Nitrophthalic Anhydride

CAS: 641-70-3

Formula: C₈H₃NO₅

Purity: >97.0%(GC)(T)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 193.11

Ref: 3B-N0245

3-Nitrophthalic anhydride, 97%

CAS: 641-70-3

4-Nitrophthalic Anhydride is an intermediate for the synthesis of the benzimidazole PARP inhibitor I, ABT-472. It reacts with aminoquinazolinones to yield phthalimidoquinazolinones. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documenta

Formula: C₈H₃NO₅

Purity: 97%

Color and Shape: White to yellow to pale brown or cream, Crystalline powder

Molecular weight: 193.11

Ref: 02-A15857

3-Nitrophthalic Anhydride

CAS: 641-70-3

Formula: C₈H₃NO₅

Purity: 97%

Color and Shape: Solid

Molecular weight: 193.1131

Ref: IN-DA0039OM

3-Nitrophthalic anhydride

CAS: 641-70-3

3-Nitrophthalic anhydride

Formula: C₈H₃NO₅

Purity: 95%

Color and Shape: yellow crystalline solid

Molecular weight: 193.11g/mol

Ref: 54-OR54546

3-Nitrophthalic anhydride

CAS: 641-70-3

3-Nitrophthalic anhydride

Formula: C₈H₃NO₅

Purity: 98%

Color and Shape: light yellow crystalline needles

Molecular weight: 193.11g/mol

Ref: 54-OR63021

3-Nitrophthalic anhydride

CAS: 641-70-3

Formula: C₈H₃NO₅

Purity: ≥ 98.0%

Color and Shape: Beige, light-yellow or yellow crystalline powder or crystals

Molecular weight: 193.11

Ref: 7W-GK0653

3-Nitrophthalic anhydride

CAS: 641-70-3

Formula: C₈H₃NO₅

Purity: 95%

Color and Shape: Crystalline Powder,Powder

Molecular weight: 193.114

Ref: 10-F078961

Pomalidomide Impurity A

CAS: 641-70-3

Formula: C₈H₃NO₅

Molecular weight: 193.11

Ref: 4Z-P-178037

3-Nitrophthalic Anhydride

CAS: 641-70-3

Formula: C₈H₃NO₅

Molecular weight: 193.11

Ref: ST-EA-CP-P25032

3-Nitrophthalic anhydride

CAS: 641-70-3

3-Nitrophthalic anhydride is a nucleophilic compound that is activated by the addition of hydrochloric acid and chloride. It reacts with dimethyl formamide to produce nitrobenzene, which can be oxidized to nitrobenzoic acid. 3-Nitrophthalic anhydride has been used as a precursor for pomalidomide, a drug used in the treatment of multiple myeloma and other cancers. In this reaction, n-dimethyl formamide reacts with 3-nitrophthalic anhydride to produce nitromethane, which can then be oxidized to nitrobenzoic acid. Molecular modeling studies have shown that 3-nitrophthalic anhydride binds to DNA through hydrogen bonding interactions and the formation of covalent bonds. The solubility data for 3-nitrophthalic anhydride show that it is soluble in water and organic solvents such as acetone or met

Formula: C₈H₃NO₅

Purity: Min. 85%

Color and Shape: Powder

Molecular weight: 193.11 g/mol

Ref: 3D-FN26343