CAS 641-80-5

17-Hydroxypregn-5-ene-3,20-dione

Description:

17-Hydroxypregn-5-ene-3,20-dione, commonly known as 17-hydroxyprogesterone, is a steroid hormone that plays a crucial role in the human endocrine system. It is a derivative of progesterone and is primarily involved in the regulation of various physiological processes, including the menstrual cycle and pregnancy. This compound is synthesized in the adrenal glands and gonads and serves as a precursor to other steroid hormones, including cortisol and androgens. In terms of its chemical structure, it features a hydroxyl group at the 17th carbon position and a double bond between the 5th and 6th carbons, which are characteristic of steroid compounds. The substance is often measured in clinical settings to assess adrenal function and diagnose conditions such as congenital adrenal hyperplasia. Its CAS number, 641-80-5, is used for identification in chemical databases. Overall, 17-hydroxyprogesterone is significant in both physiological and clinical contexts, particularly in reproductive health and endocrinology.

Formula: C₂₁H₃₀O₃

InChI: InChI=1S/C21H30O3/c1-13(22)21(24)11-8-18-16-5-4-14-12-15(23)6-9-19(14,2)17(16)7-10-20(18,21)3/h4,16-18,24H,5-12H2,1-3H3/t16-,17+,18+,19+,20+,21+/m1/s1

InChI key: InChIKey=RCFJDVCRANOZEL-CEGNMAFCSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(=CC3)CC(=O)CC4)(CC1)[H])[H])(CC[C@@]2(C(C)=O)O)[H]

Synonyms:

• 17alpha-Hydroxypregn-5-ene-3,20-dione
• Pregn-5-ene-17α-ol-3,20-dione
• Pregn-5-ene-3,20-dione, 17-hydroxy-
• 17-Hydroxypregn-5-ene-3,20-dione

Progesterone Impurity 9

CAS: 641-80-5

Formula: C₂₁H₃₀O₃

Molecular weight: 330.47

Ref: 4Z-P-3258

17-Hydroxypregn-5-ene-3,20-dione

Controlled Product

CAS: 641-80-5

Applications 17-Hydroxypregn-5-ene-3,20-dione is used in the synthesis of physiologically active steroid esters and spirolactones that functions as potential aldosterone antagonists.
References Seletskii, B. M., et al.: Croat. Chem. Acta. , 58, 699 (1986)

Formula: C₂₁H₃₀O₃

Color and Shape: Neat

Molecular weight: 330.46

Ref: TR-H952965

Progesterone Impurity 164

CAS: 641-80-5

Formula: C₂₁H₃₀O₃

Molecular weight: 330.47

Ref: ST-EA-CP-P133107