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CAS 64164-45-0

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(3beta)-25-fluorocholest-5-en-3-ol

Description:
(3beta)-25-fluorocholest-5-en-3-ol, with the CAS number 64164-45-0, is a fluorinated derivative of cholesterol, characterized by the presence of a fluorine atom at the 25th carbon position and a double bond between the 5th and 6th carbons. This compound retains the steroidal structure typical of cholesterol, which includes four fused hydrocarbon rings. The presence of the fluorine atom can significantly influence the compound's biological activity, potentially affecting its interaction with biological membranes and receptors. The hydroxyl group at the 3rd carbon contributes to its polar characteristics, enhancing solubility in certain solvents and influencing its pharmacokinetic properties. Such modifications can lead to altered metabolic pathways and biological effects, making fluorinated steroids of interest in medicinal chemistry and drug design. Overall, (3beta)-25-fluorocholest-5-en-3-ol exemplifies how small structural changes can lead to significant variations in the properties and functions of steroid compounds.
Formula:C27H45FO
InChI:InChI=1/C27H45FO/c1-18(7-6-14-25(2,3)28)22-10-11-23-21-9-8-19-17-20(29)12-15-26(19,4)24(21)13-16-27(22,23)5/h8,18,20-24,29H,6-7,9-17H2,1-5H3/t18-,20+,21+,22-,23+,24+,26+,27-/m1/s1
Synonyms:
  • 25-Fluorocholest-5-en-3beta-ol
  • Cholest-5-En-3-Ol, 25-Fluoro-, (3Beta)-
  • (3beta)-25-Fluorocholest-5-en-3-ol
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Found 1 products.
  • 25-Fluorocholesterol
    Biosynth
    + Info

    25-Fluorocholesterol

    Controlled Product
    CAS:
    <p>25-Fluorocholesterol is a hydroxylated form of cholesterol that was originally synthesized in vitro. It has been found to inhibit cholesterol synthesis and is used to study the role of cholesterol in mitochondrial function. 25-Fluorocholesterol has also been shown to possess anti-carcinogenic properties, as it inhibits adrenocortical carcinoma cells by inhibiting the production of desmosterol, which is required for their growth. This compound is also able to inhibit cho-k1 cells by side-chain cleavage. 25-Fluorocholesterol has the ability to cross cell membranes and can be detected in non-steroidal anti-inflammatory drug studies using chromatography.</p>
    Formula:C27H45FO
    Purity:Min. 95%
    Molecular weight:404.64 g/mol

    Ref: 3D-FF77345

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