2-(Iodomethyl)-1,4-dioxane is a chemical compound characterized by its unique structure, which includes a dioxane ring and an iodomethyl substituent. The presence of the dioxane moiety, a six-membered ring containing two oxygen atoms, contributes to its potential solubility in polar solvents and its reactivity in various chemical reactions. The iodomethyl group introduces a halogen, which can enhance the compound's reactivity, making it useful in organic synthesis, particularly in nucleophilic substitution reactions. This compound is typically a colorless to pale yellow liquid and may have a sweet, ether-like odor. It is important to handle 2-(iodomethyl)-1,4-dioxane with care, as it may pose health risks, including potential toxicity and irritant effects. As with many halogenated compounds, it is advisable to consider environmental impacts and regulatory guidelines when working with or disposing of this substance. Overall, its unique structural features make it a valuable intermediate in the synthesis of various organic compounds.

2-(iodomethyl)-1,4-dioxane

64179-17-5: 2-(Iodomethyl)-1,4-dioxane is a chemical compound characterized by its unique structure, which includes a dioxane ring and an iodomethyl substituent. The presence of the dioxane moiety, a six-membered ring containing two oxygen atoms, contributes to its potential solubility in polar solvents and its reactivity in various chemical reactions. The iodomethyl group introduces a halogen, which can enhance the compound's reactivity, making it useful in organic synthesis, particularly in nucleophilic substitution reactions. This compound is typically a colorless to pale yellow liquid and may have a sweet, ether-like odor. It is important to handle 2-(iodomethyl)-1,4-dioxane with care, as it may pose health risks, including potential toxicity and irritant effects. As with many halogenated compounds, it is advisable to consider environmental impacts and regulatory guidelines when working with or disposing of this substance. Overall, its unique structural features make it a valuable intermediate in the synthesis of various organic compounds.

<p>2-(iodomethyl)-1,4-dioxane is a cytotoxic moiety that binds to the capsid protein of a virus. It has been shown to be an antiviral agent against HIV-1 and other retroviruses. 2-(iodomethyl)-1,4-dioxane is hydrophobic, connecting and binds to hydrophobic regions in proteins. The compound was also observed to have antiviral activity against HIV-2 and SIV. 2-(iodomethyl)-1,4-dioxane was found to form hydrogen bonds with the capsid proteins of both HIV-1 and HIV-2, which are important for viral infectivity. This compound has been used as a linker for attaching cytotoxic molecules such as doxorubicin or camptothecin to liposomes or nanoparticles.</p>

CAS 64179-17-5

2-(iodomethyl)-1,4-dioxane

2-(iodomethyl)-1,4-dioxane

Ref: 3D-PCA17917