CAS 642-18-2

Oxayohimbanium, 3,4,5,6,16,17-hexadehydro-16-(methoxycarbonyl)-19-methyl-, inner salt, (19α,20α)-

Description:

Oxayohimbanium, specifically the compound with the CAS number 642-18-2, is a chemical substance that belongs to the class of alkaloids, derived from the yohimbine structure. It is characterized by its complex molecular framework, which includes multiple rings and functional groups, notably a methoxycarbonyl group. This compound exhibits properties typical of alkaloids, such as potential biological activity, including effects on the central nervous system and cardiovascular system. As an inner salt, it possesses both acidic and basic functional groups, allowing it to exist in a zwitterionic form under certain conditions. The presence of multiple double bonds in its structure contributes to its reactivity and stability under specific conditions. Oxayohimbanium is of interest in pharmacological research, particularly for its potential applications in treating conditions related to sexual dysfunction and other therapeutic areas. However, detailed studies on its pharmacodynamics and pharmacokinetics are essential for understanding its full potential and safety profile.

Formula: C₂₁H₂₀N₂O₃

InChI: InChI=1S/C21H20N2O3/c1-12-16-10-23-8-7-14-13-5-3-4-6-18(13)22-20(14)19(23)9-15(16)17(11-26-12)21(24)25-2/h3-8,11-12,15-16H,9-10H2,1-2H3/t12-,15-,16-/m0/s1

InChI key: InChIKey=WYTGDNHDOZPMIW-RCBQFDQVSA-N

SMILES: C(OC)(=O)C=1[C@]2(CC=3C4=C(C=5C([N-]4)=CC=CC5)C=C[N+]3C[C@]2([C@H](C)OC1)[H])[H]

Synonyms:

• Indolo[2,3-a]pyrano[3,4-g]quinolizin-6-ium, 4,4a,5,13,14,14a-hexahydro-1-(methoxycarbonyl)-4-methyl-, inner salt, (4S,4aS,14aS)-
• Oxayohimbanium, 3,4,5,6,16,17-hexadehydro-16-(methoxycarbonyl)-19-methyl-, inner salt, (19α,20α)-
• Alstonine
• Alstonine, hydroxide, inner salt

Alstonine

CAS: 642-18-2

Alstonine is a natural product that acts as a neurotransmitter and is found in the human brain. It has been shown to inhibit tumor growth in vitro and to be effective against breast cancer cells. Alstonine also inhibits glutamate-induced excitotoxicity and dopamine-induced cell death. The uptake of alstonine by neurons can be measured by NMR spectroscopy, while its synthesis can be monitored by the WST-1 assay. Alstonine can also be used as a diagnostic for cancer, due to its ability to induce apoptosis in cancer cells.

Formula: C₂₁H₂₀N₂O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 348.4 g/mol

Ref: 3D-AAA64218