CAS 642-78-4

Cloxacillin sodium

Description:

Cloxacillin sodium is a semisynthetic antibiotic belonging to the penicillin class, primarily used to treat infections caused by penicillinase-producing staphylococci. It is characterized by its ability to resist degradation by certain beta-lactamase enzymes, which makes it effective against specific bacterial strains. The compound appears as a white to off-white crystalline powder and is soluble in water, which facilitates its administration via injection. Cloxacillin sodium is typically used in the treatment of skin infections, respiratory tract infections, and other bacterial infections where staphylococcal involvement is suspected. Its mechanism of action involves inhibiting bacterial cell wall synthesis, leading to cell lysis and death. Common side effects may include gastrointestinal disturbances, allergic reactions, and, in rare cases, more severe reactions such as anaphylaxis. As with other antibiotics, it is essential to use cloxacillin sodium judiciously to prevent the development of antibiotic resistance.

Formula: C₁₉H₁₉ClN₃NaO₆S

InChI: InChI=1/C19H17Cl2N3O5S.Na.H2O/c1-7-10(12(23-29-7)11-8(20)5-4-6-9(11)21)15(25)22-13-16(26)24-14(18(27)28)19(2,3)30-17(13)24;;/h4-6,13-14,17H,1-3H3,(H,22,25)(H,27,28);;1H2/q;+1;/p-1/t13-,14?,17-;;/m1../s1

InChI key: InChIKey=JBJAWVZHLGPBJA-SLINCCQESA-N

SMILES: N(C(=O)C=1C(=NOC1C)C2=C(Cl)C=CC=C2)[C@H]3[C@@]4(N([C@@H](C(O)=O)C(C)(C)S4)C3=O)[H].[Na]

Synonyms:

• 3-(o-Chlorophenyl)-5-methyl-4-isoxazolylpenicillin sodium salt
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[3-(o-chlorophenyl)-5-methyl-4-isoxazolecarboxamido]-3,3-dimethyl-7-oxo-, monosodium salt
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-, monosodium salt, (2S,5R,6R)-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-, monosodium salt, [2S-(2α,5α,6β)]-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-, sodium salt (1:1), (2S,5R,6R)-
• 4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-, sodium salt, (2S,5R,6R)- (1:1)
• Ankerbin
• Austrastaph
• BRL 1621 sodium salt
• Cloxacillin sodium
• Cloxapen
• Ekvacillin
• Gelstaph
• Monosodium cloxacillin
• Neoclox
• Orbenin
• Orbenin sodium
• Prevencilina P
• Prostaphilin A
• Prostaphlin A
• Sodium (2S,5R,6R)-6-({[3-(2-chlorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
• Sodium 3-(O-chlorophenyl)-5-methyl-4-isoxazolylpenicillin
• Sodium cloxacillin
• Sodium orbenin
• Sodium syntarpen
• Staphybiotic
• Syntarpen sodium salt
• Tegopen
• [(5R,6R)-6-({[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylato-kappaO]sodium hydrate (1:1)
• orbeninsodium
• prevencilinap
• CLOXACILLIN SODIUM SALT HYDRATE
• brl-1621sodiumsalt
• prostaphilina
• prostaphlina
• sodiumorbenin
• 3-o-chlorophenyl-5-methyl-4-isoxazolylpenicillinsodium
• [5-METHYL-3-(O-CHLOROPHENYL)-4-ISOXAZOLYL]PENICILLIN SODIUM SALT MONOHYDRATE
• CLOXACILLIN SODIUM SALT N-HYDRATE
• CLOXACILLIN SODIUM SALT MONOHYDRATE
• 3-dimethyl-7-oxo-thyl-4-isoxazolecarboxamido)-monosodiumsalt
• monosodiumcloxacillin

Cloxacillin sodium salt

CAS: 642-78-4

A semisynthetic antibiotic

Formula: C₁₉H₁₇ClN₃NaO₅S

Color and Shape: White, Powder or crystals or crystalline powder

Molecular weight: 457.86

Ref: 02-J64314

4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-, monosodium salt, (2S,5R,6R)-

CAS: 642-78-4

Formula: C₁₉H₁₈ClN₃NaO₅S

Purity: 95%

Color and Shape: Solid

Molecular weight: 458.8711

Ref: IN-DA00JKJ7

Cloxacillin Sodium

CAS: 642-78-4

Cloxacillin Sodium: chlorinated Oxacillin derivative, semi-synthetic, treats beta-lactamase staph infections.

Formula: C₁₉H₁₇ClN₃NaO₅S

Purity: 98%

Color and Shape: White Powder

Molecular weight: 457.86

Ref: TM-T21163

Cloxacillin sodium salt

CAS: 642-78-4

Formula: C₁₉H₁₇ClN₃O₅SNa·xH₂O

Purity: (HPLC) 95.0 - 102.0 % (anhydrous basis)

Color and Shape: White or almost white, hygroscopic, powder

Molecular weight: 457.86 (anhydrous)

Ref: 7W-GA4688

Cloxacillin Sodium Salt

CAS: 642-78-4

Formula: C₁₉H₁₇ClN₃O₅S·Na

Color and Shape: White To Off-White Solid

Molecular weight: 434.88 22.99

Ref: 4Z-C-191001

Cloxacillin Sodium Salt Monohydrate

CAS: 61-72-3, 642-78-4, 7081-44-9

Formula: C₁₉H₁₇ClN₃NaO₅S·H₂O

Purity: >98.0%(HPLC)

Color and Shape: White to Orange to Green powder to crystaline

Molecular weight: 475.88

Ref: 3B-C2244

5-Hydroxy Diclofenac-d5

CAS: 642-78-4

Formula: C₁₄H₆D₅Cl₂NO₃

Molecular weight: 317.18

Ref: 4Z-D-0649

Cloxacillin Sodium Salt-13C4

CAS: 642-78-4

Formula: C₁₆₁₃C₄H₁₉ClN₃O₅S·Na

Molecular weight: 452.87 22.99

Ref: 4Z-C-191016

Cloxacillin-13C4 Sodium Salt

Controlled Product

CAS: 642-78-4

Stability Hygroscopic
Applications Labelled analogue of Cloxacillin, an antibiotic that belongs to the group of the isoxazolylpenicillins. Cloxacillin is used to treat infections caused by species of staphylococci that produce beta-lactamase due to its inhibitory effects on beta-lactamase binding.
References Gibbs, D.L. et al.: Curr. Microbiol., 2, 239 (1979); Dmitrova, D. et al.: Farmat., 48, 28 (2001); Craven, N. et al.: Res. Vet. Sci., 29, 57 (1980);

Formula: C₁₅C₄H₁₇ClN₃NaO₅S

Color and Shape: Off-White

Molecular weight: 461.83

Ref: TR-C587462

Cloxacillin Sodium Salt

CAS: 642-78-4

Applications Cloxacillin is an antibiotic that belongs to the group of the isoxazolylpenicillins. Cloxacillin is used to treat infections caused by species of staphylococci that produce beta-lactamase due to its inhibitory effects on beta-lactamase binding.
References Gibbs, D.L. et al.: Curr. Microbiol., 2, 239 (1979); Dmitrova, D. et al.: Farmat., 48, 28 (2001); CRaven, N. et al.: Res. Vet. Sci., 29, 57 (1980);

Formula: C₁₉H₁₇ClN₃O₅S·Na

Color and Shape: Off-White

Molecular weight: 457.86

Ref: TR-C587460

Cloxacillin sodium

CAS: 642-78-4

β-lactam antibiotic of penicillin subclass, which inhibits bacterial cell wall synthesis by targeting the proteoglycan synthesis. Cloxacillin has a narrow spectrum of action and is effective against Gram-positive organisms. Cloxacillin is resistant to the action of β-lactamase and therefore preferentially used for treatment of Staphylococcal infections.

Formula: C₁₉H₁₇ClN₃NaO₅S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 457.86 g/mol

Ref: 3D-AC20524

Cloxacillin-13C4 Sodium

CAS: 642-78-4

Please enquire for more information about Cloxacillin-13C4 Sodium including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₄C₁₅H₁₈ClN₃O₅S•Na

Purity: Min. 95%

Molecular weight: 462.87 g/mol

Ref: 3D-FC184004