CAS 64200-22-2

2-Propen-1-one,3-(2,4-dimethoxyphenyl)-1-(2-hydroxy-4,6-dimethoxyphenyl)-, (2E)-

Description:

2-Propen-1-one, 3-(2,4-dimethoxyphenyl)-1-(2-hydroxy-4,6-dimethoxyphenyl)-, commonly referred to by its CAS number 64200-22-2, is an organic compound characterized by its structure as a substituted chalcone. This compound features a conjugated system that includes a propenone moiety, which contributes to its potential reactivity and biological activity. The presence of multiple methoxy groups enhances its lipophilicity and may influence its interaction with biological targets. The hydroxyl group in the structure can participate in hydrogen bonding, potentially affecting its solubility and reactivity. Compounds of this nature are often studied for their antioxidant, anti-inflammatory, and anticancer properties, making them of interest in medicinal chemistry. Additionally, the specific arrangement of substituents on the aromatic rings can significantly impact the compound's electronic properties and overall stability. As with many organic compounds, the physical properties such as melting point, boiling point, and solubility would depend on the specific conditions and purity of the substance.

Formula: C₁₉H₂₀O₆

Synonyms:

• 2-Propen-1-one,3-(2,4-dimethoxyphenyl)-1-(2-hydroxy-4,6-dimethoxyphenyl)-, (E)-
• Cerasidin
• 2'-HYDROXY-2,4,4',6'-TETRAMETHOXYCHALCONE
• (2E)-3-(2,4-Dimethoxyphenyl)-1-(2-hydroxy-4,6-dimethoxyphenyl)-2-propen-1-one
• 2,4-Dimethoxyflavokawain B
• 2-Propen-1-one, 3-(2,4-dimethoxyphenyl)-1-(2-hydroxy-4,6-dimethoxyphenyl)-, (2E)-

2'-Hydroxy-2,4,4',6'-tetramethoxychalcone

CAS: 64200-22-2

2'-Hydroxy-2,4,4',6'-tetramethoxychalcone (HTMC) is a bioactive substance that has been shown to have anticancer properties. HTMC has been shown to have allopathic effects in a statistically significant manner and has been used in traditional herbal medicine for centuries. The mechanisms of action are not well understood but may be due to its ability to inhibit the activity of arjunic acid and flavonoids. HTMC is found in plants such as tropical trees and herbs from India, including Acacia catechu and Tinospora cordifolia. It also has pharmacological properties, which may be due to its derivates that are isolated from these plants. HTMC shows no adverse effects on humans when taken orally at doses up to 1 g/day for 28 days.

Formula: C₁₉H₂₀O₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 344.36 g/mol

Ref: 3D-FH66394

Cerasidin

Controlled Product

CAS: 64200-22-2

Applications Cerasidin has the general structure of chalcones (aromatic ketone and enone), and are important biological compounds. Due to this, Cerasidin has been used for cytotoxic studies, and studies involving α7 acetylcholine nicotine receptors as a possible positive allosteric modulators with other chalcone structures.
References Balsera, B., et al.: Eur. J. Med. Chem., 86, 724-39 (2014); Rajeshbabu, K.A., et al.: World Res J Pharmaceut Res., 3, 380-88 (2014);

Formula: C₁₉H₂₀O₆

Color and Shape: Neat

Molecular weight: 344.358

Ref: TR-C265530