CAS 64202-81-9

(8R,9R,12R,13R,14R,16R)-19-amino-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate

Description:

The chemical substance with the name "(8R,9R,12R,13R,14R,16R)-19-amino-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate" and CAS number "64202-81-9" is a complex organic compound characterized by its intricate bicyclic structure and multiple functional groups. It features a unique arrangement of stereocenters, which contributes to its potential biological activity. The presence of amino, hydroxy, and methoxy groups suggests that it may exhibit polar characteristics, influencing its solubility and reactivity. The compound's trioxo and carbamate functionalities indicate potential for interactions with biological macromolecules, making it of interest in medicinal chemistry. Its specific stereochemistry and functional groups may also play a crucial role in its pharmacological properties, including enzyme inhibition or receptor binding. Overall, this compound represents a fascinating example of synthetic organic chemistry with potential applications in drug development or biochemical research.

Formula: C₂₈H₃₉N₃O₈

InChI: InChI=1/C28H39N3O8/c1-14-10-18-23(29)20(32)13-19(25(18)34)31-27(35)15(2)8-7-9-21(37-5)26(39-28(30)36)17(4)12-16(3)24(33)22(11-14)38-6/h7-9,12-14,16,21-22,24,26,33H,10-11,29H2,1-6H3,(H2,30,36)(H,31,35)/b9-7+,15-8-,17-12+/t14-,16-,21-,22-,24-,26-/m1/s1

Synonyms:

• (10E)-19-amino-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
• Ipi-493

IPI-493

CAS: 64202-81-9

IPI-493 is a bioactive chemical.

Formula: C₂₈H₃₉N₃O₈

Purity: >99.99%

Color and Shape: Solid

Molecular weight: 545.62

Ref: TM-T32188

IPI-493

CAS: 64202-81-9

IPI-493

Purity: ≥98%

Molecular weight: 545.62g/mol

Ref: 54-BUP08213

17-Amino Geldanamycin-13C,15N2

Controlled Product

CAS: 64202-81-9

Applications The labelled active metabolite of 17-(Allylamino)geldanamycin (17AAG).
References Kamal, A., et al.: Nature, 425, 407 (2003), Goetz, M., et al.: J. Clin. Oncol., 23, 1078 (2005), Bagatell, R., et al.: Clin. Cancer Res., 13, 1783 (2007), Burger, A., et al.: Cancer Lett., 245, 11 (2007),

Formula: CC₂₇H₃₉₁₅N₂NO₈

Color and Shape: Neat

Molecular weight: 548.604

Ref: TR-A609702

17-Amino Geldanamycin

Controlled Product

CAS: 64202-81-9

Applications The active metabolite of 17-(Allylamino)geldanamycin (17AAG).
References Kamal, A., et al.: Nature, 425, 407 (2003), Goetz, M., et al.: J. Clin. Oncol., 23, 1078 (2005), Bagatell, R., et al.: Clin. Cancer Res., 13, 1783 (2007), Burger, A., et al.: Cancer Lett., 245, 11 (2007),

Formula: C₂₈H₃₉N₃O₈

Color and Shape: Neat

Molecular weight: 545.62

Ref: TR-A609700

17-Aminogeldanamycin

CAS: 64202-81-9

Inhibits chaperone protein Hsp90; antineoplastic

Formula: C₂₈H₃₉N₃O₈

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 545.62 g/mol

Ref: 3D-BA17365

17-Amino Geldanamycin

CAS: 64202-81-9

Formula: C₂₈H₃₉N₃O₈

Molecular weight: 545.62

Ref: ST-EA-CP-G73003