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CAS 64204-55-3

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Esaprazole

Description:
Esaprazole is a proton pump inhibitor (PPI) that is primarily used to reduce gastric acid secretion. It is characterized by its ability to inhibit the H+/K+ ATPase enzyme in the gastric parietal cells, leading to decreased production of stomach acid. This mechanism makes it effective in treating conditions such as gastroesophageal reflux disease (GERD) and peptic ulcers. Esaprazole is typically administered in oral form and is known for its relatively long half-life, allowing for once-daily dosing. The compound is generally well-tolerated, with common side effects including headache, nausea, and abdominal pain. Its chemical structure includes a pyridine ring, which contributes to its pharmacological properties. As with other PPIs, long-term use may be associated with certain risks, such as vitamin B12 deficiency and increased susceptibility to gastrointestinal infections. Overall, esaprazole represents a significant advancement in the management of acid-related disorders, providing effective symptom relief and promoting healing of the gastric mucosa.
Formula:C12H23N3O
InChI:InChI=1S/C12H23N3O/c16-12(10-15-8-6-13-7-9-15)14-11-4-2-1-3-5-11/h11,13H,1-10H2,(H,14,16)
InChI key:InChIKey=RTFADALJKSFJDZ-UHFFFAOYSA-N
SMILES:N(C(CN1CCNCC1)=O)C2CCCCC2
Synonyms:
  • 1-Piperazineacetamide, N-cyclohexyl-
  • Brn 0785765
  • C/63
  • Esaprazola
  • Esaprazola [INN-Spanish]
  • Esaprazole [INN]
  • Esaprazolum
  • Esaprazolum [INN-Latin]
  • Exaprazole
  • Hexaprazol
  • See more synonyms
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