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CAS 64225-84-9

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Tolyltetrazoliumred

Description:
Tolyltetrazolium red, also known as TTT or Toluene-2,4,5-triazole, is a chemical compound commonly used as a redox indicator in various biochemical assays. It is characterized by its ability to undergo reduction, resulting in a color change that is often utilized to assess cellular viability and metabolic activity. The compound is soluble in water and organic solvents, making it versatile for laboratory applications. Tolyltetrazolium red is particularly noted for its role in the tetrazolium assay, where it is reduced by viable cells to form a colored formazan product, allowing for quantitative analysis of cell proliferation and cytotoxicity. Its stability under physiological conditions and relatively low toxicity make it suitable for use in biological systems. However, as with any chemical, proper handling and safety precautions should be observed, as it may pose risks if ingested or improperly managed. Overall, tolyltetrazolium red is a valuable tool in the fields of biochemistry and cell biology for assessing cellular health and function.
Formula:C20H17N4
InChI:InChI=1/C20H17N4/c1-16-12-14-19(15-13-16)24-22-20(17-8-4-2-5-9-17)21-23(24)18-10-6-3-7-11-18/h2-15H,1H3/q+1
SMILES:Cc1ccc(cc1)n1nc(c2ccccc2)nn1c1ccccc1
Synonyms:
  • p-Tolyltetrazolium red
  • 3-(4-methylphenyl)-2,5-diphenyl-2H-tetrazol-3-ium
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