CAS 64232-83-3

4(1H)-Pyrimidinone,6-amino-2,3-dihydro-5-[(phenylmethylene)amino]-2-thioxo-

Description:

4(1H)-Pyrimidinone, 6-amino-2,3-dihydro-5-[(phenylmethylene)amino]-2-thioxo- is a heterocyclic organic compound characterized by its pyrimidine ring structure, which is a six-membered ring containing two nitrogen atoms. This compound features a thioxo group, indicating the presence of a sulfur atom double-bonded to a carbon atom, contributing to its reactivity and potential biological activity. The presence of an amino group enhances its ability to participate in hydrogen bonding and may influence its solubility and interaction with biological targets. The phenylmethylene group attached to the amino nitrogen suggests potential for aromatic interactions, which can be significant in drug design and molecular recognition processes. This compound may exhibit various pharmacological properties, making it of interest in medicinal chemistry. Its unique structural features allow for diverse chemical reactivity, which can be explored in synthetic applications or as a lead compound in drug discovery. Overall, this substance exemplifies the complexity and versatility of pyrimidine derivatives in organic chemistry.

Formula: C₁₁H₁₀N₄OS

6-Amino-2,3-dihydro-5-[(phenylmethylene)amino]-2-4(1H)-pyrimidineone

CAS: 64232-83-3

Formula: C₁₁H₁₀N₄OS

Purity: 98%

Color and Shape: Solid

Molecular weight: 246.2883

Ref: IN-DA00EBM6

L189

CAS: 64232-83-3

L189

Purity: ≥95%

Molecular weight: 246.29g/mol

Ref: 54-BUP05937

L189

CAS: 64232-83-3

L189 is a human DNA ligase inhibitor, inhibits hLigI/III/IV (IC50: 5/9/5 μM).

Formula: C₁₁H₁₀N₄OS

Purity: 97.37%

Color and Shape: Solid

Molecular weight: 246.29

Ref: TM-T4517

L189

Controlled Product

CAS: 64232-83-3

Applications L189 has been shown to inhibit DNA ligases I, III, and IV and may have potential use in the development of anticancer agents.
References Chen, X., et. al.: Cancer Res., 68, 3169 (2008)

Formula: C₁₁H₁₀N₄OS

Color and Shape: Neat

Molecular weight: 246.29

Ref: TR-L009020