CAS 642462-81-5

Guanosine,5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-ethyl-, 3'-[2-cyanoethylbis(1-methylethyl)phosphoramidite] (9CI)

Description:

Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-ethyl-, 3'-[2-cyanoethylbis(1-methylethyl)phosphoramidite] is a complex chemical compound primarily used in the field of nucleic acid chemistry, particularly in the synthesis of oligonucleotides. This substance features a guanosine base, which is one of the four nucleobases in RNA and DNA, linked to a phosphoramidite moiety that facilitates the stepwise assembly of nucleic acids. The presence of the bis(4-methoxyphenyl)phenylmethyl group enhances the stability and solubility of the compound, while the cyanoethyl group contributes to the reactivity necessary for oligonucleotide synthesis. The compound is characterized by its ability to form phosphodiester bonds, making it a valuable building block in the production of modified oligonucleotides for research and therapeutic applications. Its unique structure allows for specific interactions with complementary nucleic acid sequences, which is crucial for applications in gene therapy, diagnostics, and molecular biology research. Safety and handling precautions should be observed due to its chemical reactivity and potential toxicity.

Formula: C₄₂H₅₂N₇O₇P

Synonyms:

• N2-Ethyl-Dg Cep

2''-Deoxy-5''-O-DMT-N2-ethylguanosine 3''-CE phosphoramidite

CAS: 642462-81-5

Ref: 7W-GN2523

2'-Deoxy-5'-O-DMT-N2-ethylguanosine 3'-CE phosphoramidite

CAS: 642462-81-5

2'-Deoxy-5'-O-DMT-N2-ethylguanosine 3'-CE phosphoramidite is a novel nucleoside analogue. It is a nucleotide analog with potent antiviral and anticancer activities. This compound has been shown to be an activator of deoxyribonucleosides and ribonucleosides, which may lead to the activation of their respective polymerases. It also has high purity, quality, and stability, as well as being inexpensive. Rifapentine is an anti-tuberculosis drug that belongs to the class of rifamycins. It is the most active of the rifamycins for the treatment of tuberculosis. Rifapentine inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form

Formula: C₄₂H₅₂N₇O₇P

Purity: Min. 95%

Color and Shape: Solid

Molecular weight: 797.88 g/mol

Ref: 3D-PD09212