CAS 64284-64-6

4,4-Dimethyl-5α-cholesta-8,14,24-trien-3β-ol

Description:

4,4-Dimethyl-5α-cholesta-8,14,24-trien-3β-ol, with the CAS number 64284-64-6, is a sterol compound that belongs to the class of cholesterol derivatives. This substance features a complex steroid structure characterized by a tetracyclic carbon skeleton, which is typical of sterols. The presence of double bonds in the carbon chain, specifically at the 8, 14, and 24 positions, contributes to its unique reactivity and biological properties. The 4,4-dimethyl substitution indicates the presence of two methyl groups at the 4-position of the steroid nucleus, which can influence its physical and chemical properties, such as solubility and membrane fluidity. As a 3β-ol, it possesses a hydroxyl (-OH) group at the 3β position, which is crucial for its biological activity, including potential roles in cell membrane structure and signaling pathways. Overall, this compound is of interest in biochemistry and pharmacology, particularly in studies related to cholesterol metabolism and its derivatives.

Formula: C₂₉H₄₆O

InChI: InChI=1S/C29H46O/c1-19(2)9-8-10-20(3)22-12-13-23-21-11-14-25-27(4,5)26(30)16-18-29(25,7)24(21)15-17-28(22,23)6/h9,13,20,22,25-26,30H,8,10-12,14-18H2,1-7H3/t20-,22-,25+,26+,28-,29-/m1/s1

InChI key: InChIKey=LFQXEZVYNCBVDO-PBJLWWPKSA-N

SMILES: C[C@@]12C3=C(C=4[C@](C)(CC3)[C@@]([C@@H](CCC=C(C)C)C)(CC4)[H])CC[C@]1(C(C)(C)[C@@H](O)CC2)[H]

Synonyms:

• (3b,5a)-4,4-Dimethylcholesta-8,14,24-trien-3-ol
• (3beta,5alpha)-4,4-dimethyl-Cholesta-8,14,24-trien-3-ol
• 4,4-Dimethyl-5α-cholesta-8,14,24-trien-3β-ol
• Cholesta-8,14,24-trien-3-ol, 4,4-dimethyl-, (3beta,5alpha)-
• Cholesta-8,14,24-trien-3-ol, 4,4-dimethyl-, (3β,5α)-
• Ff-Mas
• Follicular fluid meiosis-activating sterol
• (3beta,5alpha)-4,4-Dimethylcholesta-8,14,24-trien-3-ol

(3R,5S,10S,13S,17S)-4,4,10,13-tetramethyl-17-[(2R)-6-methylhept-5-en-2-yl]-1,2,3,5,6,7,11,12,16,17-decahydrocyclopenta[a]phenanthren-3-ol

CAS: 64284-64-6

Formula: C₂₉H₄₆O

Color and Shape: Solid

Molecular weight: 410.6749

Ref: IN-DA00EFCJ

FF-MAS

CAS: 64284-64-6

Formula: C₂₉H₄₆O

Molecular weight: 410.69

Ref: 4Z-F-166001

(3β,5α)-4,4-Dimethylcholesta-8,14,24-trien-3-ol-d6 (Contain up to 15% δ25 isomer)

Controlled Product

CAS: 64284-64-6

Applications Labelled (3β,5α)-4,4-Dimethylcholesta-8,14,24-trien-3-ol, a follicular fluid meiosis-activating sterol (FF-MAS); a factor present in the pre-ovulatory follicle during the time of oocyte maturation. (3β,5α)-4,4-Dimethylcholesta-8,14,24-trien-3-ol has been shown to protect young oocytes from precocious chromatid separation as well as protecting aged oocytes from predivision during maturation.
References Cao, X. et al.: Biol. Reprod., 71, 1807 (2004); Cukurcam, S. et al.: Hum. Reprod., 22, 815 (2007); Bivens, C.L.M. et al.: Hum. Reprod. 19, 2340 (2004);

Formula: C₂₉H₄₀D₆O

Color and Shape: White

Molecular weight: 416.71

Ref: TR-D471727

(3β,5α)-4,4-Dimethylcholesta-8,14,24-trien-3-ol(Contain up to 15% ∆25 isomer)

Controlled Product

CAS: 64284-64-6

Applications (3β,5α)-4,4-Dimethylcholesta-8,14,24-trien-3-ol is a follicular fluid meiosis-activating sterol (FF-MAS); a factor present in the pre-ovulatory follicle during the time of oocyte maturation. (3β,5α)-4,4-Dimethylcholesta-8,14,24-trien-3-ol has been shown to protect young oocytes from precocious chromatid separation as well as protecting aged oocytes from predivision during maturation.
References Cao, X. et al.: Biol. Reprod., 71, 1807 (2004); Cukurcam, S. et al.: Human Reprod., 22, 815 (2007);

Formula: C₂₉H₄₆O

Color and Shape: Neat

Molecular weight: 410.67

Ref: TR-D471725

FF-MAS

Controlled Product

CAS: 64284-64-6

The Fluorescence-Fluoresence (FF) Microscopy Analysis System (FF-MAS) is a fluorescence microscopy system that can be used to study meiotic body formation in human oocytes. The FF-MAS is a model system for the study of physiological levels of dinucleotide phosphate, which are necessary for meiosis and maturation. This technique has been shown to be an analytical method for the evaluation of ff-mas in vitro.

Formula: C₂₉H₄₆O

Purity: Min. 95%

Molecular weight: 410.67 g/mol

Ref: 3D-PCA28464