CAS 642928-07-2: Homosildenafil
Description:Homosildenafil, with the CAS number 642928-07-2, is a synthetic compound that belongs to the class of phosphodiesterase type 5 (PDE5) inhibitors. It is structurally related to sildenafil, the active ingredient in Viagra, and is primarily investigated for its potential use in treating erectile dysfunction and pulmonary arterial hypertension. The compound works by enhancing the effects of nitric oxide, leading to increased blood flow to specific areas of the body. Homosildenafil exhibits a similar mechanism of action to other PDE5 inhibitors, promoting vasodilation and improving erectile function. Its pharmacokinetic properties, including absorption, distribution, metabolism, and excretion, are essential for determining its efficacy and safety profile. As with other medications in this class, potential side effects may include headaches, flushing, and gastrointestinal disturbances. Research into homosildenafil continues to explore its therapeutic applications and optimize its formulation for clinical use. However, as of the latest updates, it remains primarily a subject of scientific investigation rather than a widely prescribed medication.
Formula:C23H32N6O4S
InChI:InChI=1S/C23H32N6O4S/c1-5-8-18-20-21(27(4)26-18)23(30)25-22(24-20)17-15-16(9-10-19(17)33-7-3)34(31,32)29-13-11-28(6-2)12-14-29/h9-10,15H,5-8,11-14H2,1-4H3,(H,24,25,30)
InChI key:InChIKey=MJEXYQIZUOHDGY-UHFFFAOYSA-N
SMILES:O=C1N=C(NC=2C(=NN(C12)C)CCC)C=3C=C(C=CC3OCC)S(=O)(=O)N4CCN(CC)CC4
- Synonyms:
- 7H-Pyrazolo[4,3-d]pyrimidin-7-one, 5-[2-ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-
- 5-[2-Ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one
- Homosildenafil
- Piperazine, 1-[[3-(4,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-ethyl-
