CAS 64297-16-1
:parathyroid hormone fragment*nle8,18,tyr34-amide
Description:
Parathyroid hormone fragment *nle8,18,tyr34-amide, identified by the CAS number 64297-16-1, is a synthetic peptide that represents a modified form of parathyroid hormone (PTH). This fragment is characterized by specific amino acid substitutions, notably the incorporation of non-leucine (nle) residues at positions 8 and 18, and a tyrosine (tyr) at position 34, with an amide group at the C-terminus. These modifications enhance its biological activity and stability compared to the native hormone. Parathyroid hormone plays a crucial role in calcium homeostasis and bone metabolism, primarily by regulating calcium levels in the blood and influencing bone remodeling processes. The fragment's structure allows it to interact with PTH receptors, promoting osteoblast activity and increasing renal tubular reabsorption of calcium. As a research tool, this peptide is often utilized in studies related to bone health, osteoporosis, and calcium regulation, providing insights into therapeutic applications for metabolic bone diseases.
Formula:C177H279N53O48
Synonyms:- Parathyroid hormone (3-34) amide, nle(8,18),nle(34)-
- (Nle-8,nle-18,tyr-34)bpth-(3-34) amide
- 8,18-Nle-34-tyr bovine parathyroid hormone (3-34) amide
- 8,18-Nle-34-tyr-bpth (3-34) amide
- 8,18-Norleucyl-34-tyrosine-bovine parathyroid hormone (3-34) amide
- Bovine parathyroid hormone (3-34) amide, 8,18-nle-34-tyr-
- Bovine parathyroid hormone (3-34)-amide, 8,18-norleucyl-34-tyrosine-
- Bpth (3-34) amide, 8,18-nle-34-tyr-
- Hpth, nle(8,18)-tyr(34)-
- Sbpth-(3-34)-A
- L-Tyrosinamide, L-seryl-L-alpha-glutamyl-L-isoleucyl-L-glutaminyl-L-phenylalanyl-L-norleucyl-L-histidyl-L-asparaginyl-L-leucylglycyl-L-lysyl-L-histidyl-L-leucyl-L-seryl-L-seryl-L-norleucyl-L-alpha-glutamyl-L-arginyl-L-valyl-L-alpha-glutamyl-L-tryptophyl-L-leucyl-L- arginyl-L-lysyl-L-lysyl-L-leucyl-L-glutaminyl-L-alpha-aspartyl-L-valyl-L-histidyl-L-asparaginyl-
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Found 1 products.
(Nle 8·18,Tyr34)-pTH (3-34) amide (bovine)
CAS:<p>Please enquire for more information about (Nle 8·18,Tyr34)-pTH (3-34) amide (bovine) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C177H279N53O48Purity:Min. 95%Molecular weight:3,917.44 g/mol
