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CAS 643-22-1

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erythromycin stearate

Description:
Erythromycin stearate is an antibiotic belonging to the macrolide class, primarily used to treat various bacterial infections. It is a stearate salt of erythromycin, which enhances its stability and solubility. The compound typically appears as a white to off-white powder and is characterized by its relatively low solubility in water, making it more suitable for oral administration in solid dosage forms. Erythromycin stearate exhibits a broad spectrum of activity against gram-positive bacteria and some gram-negative bacteria, as well as atypical pathogens. Its mechanism of action involves inhibiting bacterial protein synthesis by binding to the 50S ribosomal subunit. The substance is generally well-tolerated, though it may cause gastrointestinal side effects in some patients. Erythromycin stearate is often used in cases where patients are allergic to penicillin or when penicillin is not effective. As with all antibiotics, appropriate use is essential to minimize the risk of resistance development.
Formula:C55H103NO15
InChI:InChI=1/C55H101NO14/c1-15-17-18-19-20-21-22-23-24-25-26-27-28-29-30-31-43(57)68-47-41(56(12)13)32-36(4)65-52(47)70-50-38(6)46(69-44-34-54(10,64-14)49(60)40(8)66-44)39(7)51(61)67-42(16-2)55(11,63)48(59)37(5)45(58)35(3)33-53(50,9)62/h35-42,44,46-50,52,59-60,62-63H,15-34H2,1-14H3/t35-,36-,37+,38+,39-,40+,41+,42-,44+,46+,47-,48-,49+,50-,52+,53-,54-,55-/m1/s1
InChI key:InChIKey=YAVZHCFFUATPRK-YZPBMOCRSA-N
SMILES:O([C@@H]1[C@@H](C)[C@H](O[C@H]2C[C@](OC)(C)[C@@H](O)[C@H](C)O2)[C@@H](C)C(=O)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@]1(C)O)[C@H]3[C@H](O)[C@@H](N(C)C)C[C@@H](C)O3.C(CCCCCCCCCCC)CCCCCC(O)=O
Synonyms:
  • (2S,3R,4S,6R)-4-(dimethylamino)-2-{[(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-2,10-dioxooxacyclotetradecan-6-yl]oxy}-6-methyltetrahydro-2H-pyran-3-yl octadecanoate (non-preferred name)
  • Abboticine
  • Bristamycin
  • Ccris 1504
  • Dowmycin E
  • Eratrex
  • Erypar
  • Eryprim
  • Erythro S
  • Erythrocin stearate
  • See more synonyms
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