CAS 64318-79-2
:Gemeprost
Description:
Gemeprost is a synthetic prostaglandin E1 analog, primarily used in medical applications, particularly in obstetrics and gynecology. It is characterized by its ability to induce cervical ripening and facilitate uterine contractions, making it valuable in labor induction and medical abortion. Gemeprost acts by binding to specific prostaglandin receptors, leading to smooth muscle relaxation and increased uterine activity. The substance is typically administered via vaginal or oral routes, depending on the clinical context. Its pharmacological effects include promoting cervical dilation and enhancing uterine contractility, which are crucial for effective labor management. Gemeprost is generally well-tolerated, but like other prostaglandins, it may cause side effects such as gastrointestinal disturbances, headache, or uterine hyperstimulation. Due to its potent effects, its use is carefully monitored in clinical settings to ensure patient safety and efficacy. As with any medication, it is essential to consider contraindications and potential interactions with other drugs when prescribing Gemeprost.
Formula:C23H38O5
InChI:InChI=1S/C23H38O5/c1-5-6-15-23(2,3)21(26)14-13-18-17(19(24)16-20(18)25)11-9-7-8-10-12-22(27)28-4/h10,12-14,17-18,20-21,25-26H,5-9,11,15-16H2,1-4H3/b12-10+,14-13+/t17-,18-,20-,21-/m1/s1
InChI key:InChIKey=KYBOHGVERHWSSV-VNIVIJDLSA-N
SMILES:C(=C/[C@H](C(CCCC)(C)C)O)\[C@@H]1[C@@H](CCCC/C=C/C(OC)=O)C(=O)C[C@H]1O
Synonyms:- (2E,11alpha,13E,15R)-11,15-Dihydroxy-16,16-dimethyl-9-oxoprosta-2,13-dien-1-oic acid, methyl ester
- 16,16-Dimethyl-trans-delta(sup 2)-prostaglandin E1 methyl ester
- 16,16-Dimethyl-trans-delta-2-PGE1 methyl ester
- 16,16-Dimethyl-trans-delta-2-prostaglandin e1 methyl ester
- 16,16-Dimethyl-trans-Δ<sup>2</sup>-PGE methyl ester
- 16,16-Dimethyl-trans-Δ<sup>2</sup>-PGE<sub>1</sub> methyl ester
- 16,16-Dimethyl-trans-Δ<sup>2</sup>-prostaglandin E<sub>1</sub> methyl ester
- Carprost
- Cergem
- Cervagem
- Cervageme
- Gemeprostum
- Gemeprostum [INN-Latin]
- Methyl (E)-7-((1R,2R,3R)-3-hydroxy-2-((E)-(3R)-3-hydroxy-4,4-dimethyl-1-octenyl)-5-oxocyclopentyl)-2-heptenoate
- Methyl 16,16-dimethyl-trans-delta-2-PGE1
- Methyl 16,16-dimethyl-trans-Δ<sup>2</sup>-PGE<sub>1</sub>
- Ono 802
- Preglandin
- Prosta-2,13-dien-1-oic acid, 11,15-dihydroxy-16,16-dimethyl-9-oxo-, methyl ester, (2E,11alpha,13E,15R)-
- Prosta-2,13-dien-1-oic acid, 11,15-dihydroxy-16,16-dimethyl-9-oxo-, methyl ester, (2E,11α,13E,15R)-
- Sc 37681
- Unii-45Kzb1Fols
- methyl (2E,11alpha,13E,15R)-11,15-dihydroxy-16,16-dimethyl-9-oxoprosta-2,13-dien-1-oate
- methyl (2E,8beta,11beta,12alpha,13Z,15R)-11,15-dihydroxy-16,16-dimethyl-9-oxoprosta-2,13-dien-1-oate
- trans-2,3-Didehydro-16,16-dimethyl PGE1 methyl ester
- trans-2,3-Didehydro-16,16-dimethyl PGE<sub>1</sub> methyl ester
- 16,16-Dimethyl-trans-Δ2-prostaglandin E1 methyl ester
- See more synonyms
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