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CAS 64332-33-8

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D-Streptamine,O-6-amino-2-[(aminocarbonyl)amino]-2,3,6-trideoxy-a-D-ribo-hexopyranosyl-(1®4)-O-[3-amino-3-deoxy-a-D-glucopyranosyl-(1®6)]-2-deoxy- (9CI)

Description:
D-Streptamine, O-6-amino-2-[(aminocarbonyl)amino]-2,3,6-trideoxy-α-D-ribo-hexopyranosyl-(1→4)-O-[3-amino-3-deoxy-α-D-glucopyranosyl-(1→6)]-2-deoxy- (9CI), with the CAS number 64332-33-8, is a complex aminoglycoside antibiotic. This compound is characterized by its unique sugar structure, which includes multiple deoxy sugars linked through glycosidic bonds. The presence of amino and aminocarbonyl functional groups contributes to its biological activity, particularly its ability to inhibit bacterial protein synthesis by binding to the ribosomal RNA. D-Streptamine exhibits a specific stereochemistry that is crucial for its interaction with bacterial ribosomes. Its solubility and stability can vary depending on the pH and ionic strength of the solution. This compound is of interest in medicinal chemistry due to its potential therapeutic applications, particularly in treating infections caused by Gram-negative bacteria. However, like many aminoglycosides, it may also exhibit nephrotoxicity and ototoxicity, necessitating careful consideration in clinical use.
Formula:C19H38N6O10
Synonyms:
  • Nebramycinfactor 11
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