CAS 644-62-2

Meclofenamic acid

Description:

Meclofenamic acid is a non-steroidal anti-inflammatory drug (NSAID) primarily used for its analgesic and anti-inflammatory properties. It belongs to the fenamate class of NSAIDs and is characterized by its ability to inhibit cyclooxygenase enzymes, which play a crucial role in the synthesis of prostaglandins involved in inflammation and pain. The chemical formula of meclofenamic acid is C15H14ClN and it features a chlorobenzene ring, a phenyl group, and a carboxylic acid functional group, contributing to its pharmacological activity. It is typically administered in oral form and is indicated for the treatment of conditions such as arthritis and dysmenorrhea. Meclofenamic acid is known for its potential side effects, which may include gastrointestinal disturbances, cardiovascular risks, and renal impairment, necessitating careful monitoring during use. Additionally, it is important to consider contraindications and interactions with other medications. Overall, meclofenamic acid is a potent anti-inflammatory agent with a specific chemical structure that underpins its therapeutic effects.

Formula: C₁₄H₁₁Cl₂NO₂

InChI: InChI=1/C14H11Cl2NO2.Na/c1-8-6-7-10(15)13(12(8)16)17-11-5-3-2-4-9(11)14(18)19;/h2-7,17H,1H3,(H,18,19);/q;+1/p-1

InChI key: InChIKey=SBDNJUWAMKYJOX-UHFFFAOYSA-N

SMILES: N(C1=C(Cl)C(C)=CC=C1Cl)C2=C(C(O)=O)C=CC=C2

Synonyms:

• 2-[(2,6-Dichloro-3-methylphenyl)amino]benzoic acid
• Acide Meclofenamique
• Acido Meclofenamico
• Anthranilic acid, N-(2,6-dichloro-m-tolyl)-
• Arquel
• Inf 4668
• Meclofenamic Acid
• Meclofenamicsaure
• Meclophenamic acid
• N-(2,6-Dichloro-3-methylphenyl)anthranilic acid
• N-(2,6-Dichloro-m-tolyl)anthranilic acid
• N-(3-Methyl-2,6-dichlorophenyl)anthranilic acid
• Nsc 95309
• Meclomen
• sodium 2-[(2,6-dichloro-3-methylphenyl)amino]benzoate
• Meclofen
• Benzoic acid, 2-[(2,6-dichloro-3-methylphenyl)amino]-
• 2-(2,6-dichloro-3-methyl-anilino)benzoic acid
• Meclorfenamic
• 2-(2,6-dichloro-3-methylanilino)benzoic acid

Meclofenamic Acid

CAS: 644-62-2

Color and Shape: Neat

Ref: 61-FOR3124.00

2-((2,6-Dichloro-3-methylphenyl)amino)benzoic acid

CAS: 644-62-2

2-((2,6-Dichloro-3-methylphenyl)amino)benzoic acid

Purity: 95%

Molecular weight: 296.15g/mol

Ref: 54-OR1073263

Meclofenamic acid

Controlled Product

CAS: 644-62-2

Formula: C₁₄H₁₁Cl₂NO₂

Color and Shape: Neat

Molecular weight: 296.15

Ref: 04-C14804500

Meclofenamic Acid

Controlled Product

CAS: 644-62-2

Formula: C₁₄H₁₁Cl₂NO₂

Color and Shape: Neat

Molecular weight: 296.15

Ref: 86-MM3124.00

Meclofenamic Acid

Controlled Product

CAS: 644-62-2

Applications Meclofenamic Acid is anti-inflammatory. It is used as an antipyretic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Juby, et al.: J. Med. Chem., 11, 111 (1968), Winder, et al.: J. Pharmacol. Exp. Ther., 148, 422 (1965), Rees, M.C.P., et al.: Lancet, 2, 541 (1988),

Formula: C₁₄H₁₁Cl₂NO₂

Color and Shape: Neat

Molecular weight: 296.15

Ref: TR-M202750

Meclofenamic acid

CAS: 644-62-2

Meclofenamic acid is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits the activity of cyclooxygenase and lipoxygenase. It is used for the treatment of mild to moderate pain, dysmenorrhea, and menstrual cramps. Meclofenamic acid binds to polymerase chain reaction (PCR) substrate-binding site, inhibiting DNA synthesis in rat hippocampal neurons. This drug has also been shown to suppress disease activity in animals with experimental arthritis. Meclofenamic acid can be administered orally or intravenously without altering its effect on disease activity or blood sampling results. The drug is rapidly metabolized by hydroxylation and conjugation with glucuronic acid, followed by excretion in urine or feces. Meclofenamic acid significantly cytotoxic to human polymorphonuclear leukocytes at high concentrations, which may be due to its ability to modify RNA synthesis and protein synthesis.

Formula: C₁₄H₁₁Cl₂NO₂

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 296.15 g/mol

Ref: 3D-FM25028

Meclofenamic acid

CAS: 644-62-2

Meclofenamic acid: non-selective gap-junction blocker, FTO inhibitor, anti-inflammatory.

Formula: C₁₄H₁₁Cl₂NO₂

Purity: 99.98%

Color and Shape: Solid

Molecular weight: 296.15

Ref: TM-T11990