CAS 644-78-0

2-Hydroxychalcone

Description:

2-Hydroxychalcone, with the CAS number 644-78-0, is a flavonoid compound characterized by its structural features, which include a chalcone backbone with a hydroxyl group at the second position of the aromatic ring. This compound typically appears as a pale yellow solid and is known for its potential biological activities, including antioxidant, anti-inflammatory, and antimicrobial properties. It is soluble in organic solvents like ethanol and methanol but has limited solubility in water. The presence of the hydroxyl group enhances its reactivity and interaction with various biological targets. 2-Hydroxychalcone is often studied in the context of medicinal chemistry and natural product research due to its ability to modulate various biochemical pathways. Additionally, it serves as a precursor for the synthesis of other flavonoids and can be utilized in the development of functional foods and nutraceuticals. Its stability and reactivity can be influenced by environmental factors such as pH and temperature, making it an interesting subject for further research in both synthetic and applied chemistry.

Formula: C₁₅H₁₂O₂

InChI: InChI=1/C15H12O2/c16-14-9-5-4-8-13(14)15(17)11-10-12-6-2-1-3-7-12/h1-11,16H/b11-10-

InChI key: InChIKey=UDOOPSJCRMKSGL-UHFFFAOYSA-N

SMILES: C(=CC(=O)C1=CC=CC=C1)C2=C(O)C=CC=C2

Synonyms:

• (2-Hydroxybenzylidene)acetophenone~3-(2-Hydroxyphenyl)-1-phenyl-2-propen-1-one
• (2E)-3-(2-hydroxyphenyl)-1-phenylprop-2-en-1-one
• (2Z)-1-(2-hydroxyphenyl)-3-phenylprop-2-en-1-one
• 1-Phenyl-3-(2-hydroxyphenyl)-2-propenone
• 2-Hydroxychalcone, [(2-Hydroxybenzylidene)- acetopheno
• 2-Propen-1-one, 3-(2-hydroxyphenyl)-1-phenyl-
• 3-(2-Hydroxyphenyl)-1-Phenylprop-2-En-1-One
• 3-(2-Hydroxyphenyl)-1-phenyl-2-propen-1-one
• 3-(2-Hydroxyphenyl)-1-phenylpropenone
• 3-(o-Hydroxyphenyl)acrylophenone
• Chalcone, 2-hydroxy-
• NSC 37432
• NSC 640539
• Salicylideneacetophenone
• o-Hydroxystyryl phenyl ketone
• 2-Hydroxychalcone
• 2-(2-HYDROXYBENZYLIDENE)ACETOPHENONE
• 2-(2-HYDROXYBENZAL)ACETOPHENONE
• TRANS-2-HYDROXYBENZYLIDENEACETOPHENONE
• 2-Hydroxychalcone, 98+%
• BENZYLIDENE-2-HYDROXYACETOPHENONE
• SALICYLALACETOPHENONE
• α-(o-Hydroxybenzylidene)acetophenone
• o-Hydroxychalcone
• 2-HYDROXYCHALCONE(UNSPECIFIEDISOMER)
• 2-HYDROXYBENZYLIDENE ACETOPHENONE
• TRANS-2-HYDROXYCHALCONE
• HYDROXYCHALCONE, 2-

(E)-2-Hydroxychalcone

CAS: 42224-53-3, 644-78-0

Formula: C₁₅H₁₂O₂

Purity: >98.0%(GC)(T)

Color and Shape: Light yellow to Amber to Dark green powder to crystal

Molecular weight: 224.26

Ref: 3B-H0234

2-Hydroxychalcone, 98+%

CAS: 644-78-0

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₅H₁₂O₂

Purity: 98+%

Color and Shape: Powder, Yellow to green

Molecular weight: 224.26

Ref: 02-A12851

2-Hydroxychalcone

CAS: 644-78-0

2-Hydroxychalcone analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Formula: C₁₅H₁₂O₂

Purity: (HPLC) ≥95%

Color and Shape: Powder

Molecular weight: 224.27

Ref: 11-1270

3-(2-Hydroxyphenyl)-1-phenylprop-2-en-1-one

CAS: 644-78-0

Formula: C₁₅H₁₂O₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 224.2546

Ref: IN-DA003HFF

2-Hydroxychalcone

CAS: 644-78-0

2-Hydroxychalcone

Formula: C₁₅H₁₂O₂

Purity: 98%

Color and Shape: yellow powder

Molecular weight: 224.25g/mol

Ref: 54-OR8852

2-Hydroxychalcone

CAS: 644-78-0

2-Hydroxychalcone

Purity: ≥98%

Molecular weight: 224.25g/mol

Ref: 54-BUP16479

2-Hydroxychalcone

CAS: 644-78-0

2-Hydroxychalcone (2-(2-Hydroxybenzal)Acetophenone) can be used as antiparasitic hit compounds when Methoxylated. It inhibits invasion of breast cancer cells.

Formula: C₁₅H₁₂O₂

Purity: 99.6%

Color and Shape: Solid

Molecular weight: 224.25

Ref: TM-T7979

2-Hydroxychalcone

CAS: 644-78-0

2-Hydroxychalcone is a chemical compound that has been shown to have hypoglycemic effects in mice and rats. It also inhibits the efflux pump of cancer cells, which prevents the drug from being pumped out of the cell, and thus increases its concentration inside the cell. 2-Hydroxychalcone is structurally similar to epidermal growth factor (EGF). The nitrogen atoms are important for its activity as they can form hydrogen bonds with water molecules and help stabilize the protein's conformation. 2-Hydroxychalcone has been shown to have anti-cancer properties in vitro and in vivo, with a particular effect on prostate cancer cells. It also inhibits tumor growth by reducing the production of insulin-like growth factor 1 (IGF1) levels.

Formula: C₁₅H₁₂O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 224.25 g/mol

Ref: 3D-FH43279

2-Hydroxychalcone

CAS: 644-78-0

Formula: C₁₅H₁₂O₂

Purity: 98.0%

Color and Shape: Solid

Molecular weight: 224.259

Ref: 10-F003115