CAS 64419-06-3

4-Deoxy-20-hydroxy-4-[2-(1-hydroxyethyl)-1-pyrrolidinyl]rifamycin

Description:

4-Deoxy-20-hydroxy-4-[2-(1-hydroxyethyl)-1-pyrrolidinyl]rifamycin, with the CAS number 64419-06-3, is a synthetic derivative of rifamycin, a class of antibiotics known for their efficacy against bacterial infections, particularly tuberculosis. This compound features a complex structure characterized by a rifamycin core, which includes a naphthalenic ring system and a hydroxyl group at the 20-position, contributing to its biological activity. The presence of a pyrrolidine ring with a hydroxyethyl substituent enhances its pharmacological properties, potentially improving its solubility and bioavailability. As a member of the rifamycin family, it likely exhibits mechanisms of action that involve the inhibition of bacterial RNA synthesis by binding to DNA-dependent RNA polymerase. The compound's specific characteristics, including its stability, solubility, and interaction with biological systems, are critical for its therapeutic applications. Further studies would be necessary to fully elucidate its pharmacokinetics, efficacy, and safety profile in clinical settings.

Formula: C₄₃H₅₈N₂O₁₃

Synonyms:

• Rifamycin, 4-deoxy-20-hydroxy-4-[2-(1-hydroxyethyl)-1-pyrrolidinyl]-
• 4-Deoxy-20-hydroxy-4-[2-(1-hydroxyethyl)-1-pyrrolidinyl]rifamycin
• Halomicin C
• 2,7-(Epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan,rifamycin deriv.
• Halomicin C

Halomicin C

CAS: 64419-06-3

Halomicin C is an ansamycin antibiotic effective against both Gram-positive and Gram-negative bacteria.

Formula: C₄₃H₅₈N₂O₁₃

Color and Shape: Solid

Molecular weight: 810.926

Ref: TM-TN9944