CAS 64480-66-6

Glycoursodeoxycholic acid

Description:

Glycoursodeoxycholic acid, with the CAS number 64480-66-6, is a bile acid derivative that plays a role in the digestion and absorption of fats and fat-soluble vitamins in the intestine. It is a conjugated bile acid formed by the conjugation of ursodeoxycholic acid with glycine. This compound exhibits amphipathic properties, meaning it has both hydrophilic and hydrophobic regions, which facilitates its function as a detergent in the emulsification of lipids. Glycoursodeoxycholic acid is known for its potential therapeutic effects, particularly in the treatment of liver diseases and gallstone dissolution. It may also possess cytoprotective properties, helping to protect liver cells from damage. In terms of solubility, it is generally soluble in water due to its polar functional groups. Its molecular structure includes a steroid backbone with hydroxyl groups that contribute to its biological activity. Overall, glycoursodeoxycholic acid is significant in both physiological processes and potential clinical applications.

Formula: C₂₆H₄₃NO₅

InChI: InChI=1S/C26H43NO5/c1-15(4-7-22(30)27-14-23(31)32)18-5-6-19-24-20(9-11-26(18,19)3)25(2)10-8-17(28)12-16(25)13-21(24)29/h15-21,24,28-29H,4-14H2,1-3H3,(H,27,30)(H,31,32)/t15-,16+,17-,18-,19+,20+,21+,24+,25+,26-/m1/s1

InChI key: InChIKey=GHCZAUBVMUEKKP-XROMFQGDSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](C[C@@H]3O)(C[C@H](O)CC4)[H])(CC1)[H])[H])(CC[C@@]2([C@@H](CCC(NCC(O)=O)=O)C)[H])[H]

Synonyms:

• 2-[[(4R)-4-[(3R,5S,7S,10R,13R,17R)-3,7-Dihydroxy-10,13-Dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-Tetradecahydro-1H-Cyclopenta[A]Phenanthren-17-Yl]Pentanoyl]Amino]Acetic Acid
• 3α,7β-Dihydroxy-5β-cholanoylglycine
• Glycine, N-[(3α,5β,7β)-3,7-dihydroxy-24-oxocholan-24-yl]-
• Glycoursodeoxycholic acid
• Glycylursodeoxycholic acid
• N-(3α,7β-Dihydroxy-5β-cholan-24-oyl)glycine
• N-[(3α,5β,7β)-3,7-Dihydroxy-24-oxocholan-24-yl]glycine
• Ursodeoxycholylglycine
• Glycine ursodeoxycholic acid
• GUDCA
• 3.alpha.,7.beta.-Dihydroxy-5.beta.-cholanoylglycine
• N-Carboxymethyl-3α,7β-dihydroxy-5β-cholan-24-amide
• 3.α.,7.beta.-Dihydroxy-5.beta.-cholanoylglycine
• N-[(3.α.,5.beta.,7.beta.)-3,7-dihydroxy-24-oxocholan-24-yl]Glycine
• N-[(3.alpha.,5.beta.,7.beta.)-3,7-Dihyd
• N-[(3α,5β,7β)-3,7-Dihydroxy-24-oxocholan-24-yl]glycine, Glycylursodeoxycholic acid
• N-[(3.α.,5.beta.,7.beta.)-3,7-Dihyd
• N-[(3.alpha.,5.beta.,7.beta.)-3,7-dihydroxy-24-oxocholan-24-yl]Glycine
• N-(3α,7β-Dihydroxy-24-oxo-5β-cholan-24-yl)glycine
• N-((3alpha,5beta,7beta)-7-Hydroxy-24-oxo-3-(sulfooxy)cholan-24-yl)glycine
• N-(3.α.,7.beta.-Dihydroxy-5.beta.-cholan-24-oyl)glycine
• N-(3.alpha.,7.beta.-Dihydroxy-5.beta.-cholan-24-oyl)glycine
• 3-amino-1-azabicyclo[2.2.2]oct-3-yl diphenylacetate hydrochloride(1:1)
• Glycoursodeoxycholic-d4 Acid

Glycoursodeoxycholic Acid

CAS: 64480-66-6

Formula: C₂₆H₄₃NO₅

Purity: >95.0%(HPLC)(N)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 449.63

Ref: 3B-G0459

Glycoursodeoxycholic acid

CAS: 64480-66-6

Formula: C₂₆H₄₃NO₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 449.6233

Ref: IN-DA0036XT

Glycoursodeoxycholic Acid-d7

CAS: 64480-66-6

Formula: C₂₆H₃₈D₅NO₅

Molecular weight: 456.67

Ref: 4Z-U-027

Glycoursodeoxycholic acid

CAS: 64480-66-6

Glycoursodeoxycholic acid

Purity: ≥98%

Molecular weight: 449.62g/mol

Ref: 54-BUP00193

Glycoursodeoxycholic Acid

CAS: 64480-66-6

Formula: C₂₆H₄₃NO₅

Color and Shape: White To Off-White Solid

Molecular weight: 449.63

Ref: 4Z-U-026

Glycoursodeoxycholic acid

CAS: 64480-66-6

Formula: C₂₆H₄₃NO₅

Purity: 95%~99%

Molecular weight: 449.632

Ref: BP-SBP03993

Glycoursodeoxycholic acid

CAS: 64480-66-6

Purity: 98%

Molecular weight: 449.6319885253906

Ref: 10-F787625

Glycoursodeoxycholic acid

CAS: 64480-66-6

Glycoursodeoxycholic acid, a secondary bile acid-glycine conjugate, is formed by colonic microbes and found in mammalian bile.

Formula: C₂₆H₄₃NO₅

Purity: 99.62% - 99.89%

Color and Shape: Solid

Molecular weight: 449.62

Ref: TM-T5234

Glycoursodeoxycholic acid

CAS: 64480-66-6

Formula: C₂₆H₄₃NO₅

Purity: ≥ 97.0%

Color and Shape: White to almost white powder

Molecular weight: 449.62

Ref: 7W-GL1421

Glycoursodeoxycholic Acid-d5

Controlled Product

CAS: 64480-66-6

Applications Stable labelled metabolite of Ursodeoxycholic Acid, which is used as an anticholelithogenic.

Formula: C₂₆H₃₈D₅NO₅

Color and Shape: Off-White

Molecular weight: 454.65

Ref: TR-G679552

Glycoursodeoxycholic Acid

CAS: 64480-66-6

Applications A metabolite of Ursodeoxycholic Acid, which is used as an anticholelithogenic.

Formula: C₂₆H₄₃NO₅

Color and Shape: White To Off-White

Molecular weight: 449.62

Ref: TR-G679550

Glycoursodeoxycholic acid

CAS: 64480-66-6

Glycoursodeoxycholic acid (GUDCA) is a bile acid that is synthesized from glycine and ursodeoxycholic acid. It has been shown to have an antioxidant effect in a model system of oxidative injury. GUDCA has also been found to attenuate the effects of bile acid on bowel disease, as well as metabolic disorders such as energy metabolism and bile acid homeostasis. GUDCA may be used as a therapeutic treatment for metabolic disorders, including obesity and diabetes. GUDCA may also be effective in treating neurological diseases such as Alzheimer's disease and Parkinson's disease.

Formula: C₂₆H₄₃NO₅

Purity: Min. 96 Area-%

Color and Shape: White Powder

Molecular weight: 449.62 g/mol

Ref: 3D-FG23694

Glycoursodeoxycholic Acid (GUDCA) extrapure, 97%

CAS: 64480-66-6

Formula: C₂₆H₄₃NO₅

Molecular weight: 449.62

Ref: SR-50391

Glycoursodeoxycholic Acid

CAS: 64480-66-6

Formula: C₂₆H₄₃NO₅

Molecular weight: 449.63

Ref: ST-EA-CP-U1019