CAS 64485-93-4

Cefotaxime sodium

Description:

Cefotaxime sodium is a broad-spectrum cephalosporin antibiotic used primarily for the treatment of bacterial infections. It is effective against a variety of Gram-positive and Gram-negative bacteria, making it a valuable option in clinical settings. The compound is typically administered via injection and is known for its good tissue penetration and ability to cross the blood-brain barrier, which is particularly beneficial in treating central nervous system infections. Cefotaxime sodium works by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. It is generally well-tolerated, but potential side effects may include allergic reactions, gastrointestinal disturbances, and alterations in blood cell counts. The drug is often used in cases of pneumonia, urinary tract infections, and sepsis. Its stability in solution and compatibility with various intravenous fluids make it a practical choice for hospital use. As with all antibiotics, appropriate susceptibility testing is recommended to ensure effectiveness against specific pathogens.

Formula: C₁₆H₁₇N₅O₇S₂·Na

InChI: InChI=1S/C16H17N5O7S2.Na/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8;/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26);/b20-9-;/t10-,14-;/m1./s1

InChI key: InChIKey=UWNYOXHAYFLGIE-JUZDKLSSSA-N

SMILES: C(O)(=O)C=1N2[C@@]([C@H](NC(/C(=N\OC)/C=3N=C(N)SC3)=O)C2=O)(SCC1COC(C)=O)[H].[Na]

Synonyms:

• (6R-(6Alpha,7Beta(Z)))-3-((Acetyloxy)Methyl)-(((2-Amine-4-Thiazolyl)(Methoxyimino)Acetyl)Amino)-8-Oxo-5-Thia-1-Azabicyclo(4,2,0)Oct-2-Ene-2-Carboxylic Acid Monosodium Salt
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-, monosodium salt, [6R-[6α,7β(Z)]]-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-, monosodium salt, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-8-oxo-, sodium salt (1:1), (6R,7R)-
• 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[(2E)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)-1-oxoethyl]amino]-8-oxo-, sodium salt, (6R,7R)- (1:1)
• Baxim
• Biolog
• Biotax
• Bioxim
• Calcef
• Califrid
• CefSo
• Cefacron
• Cefantral
• Cefcan
• Cefomed
• Cefomerc
• Cefomerk
• Cefon
• Cefotam
• Cefotax
• Cefotaxim Sodium
• Cefotaxime sodium
• Cefotaxime sodium salt
• Cefoxim
• Cefronate
• Ceftim
• Ceftop
• Ceftoringe
• Chemcef
• Clafora
• Claforan
• Claftax
• Clavox
• Eaxiron
• Elkotak
• Epotazime
• Evotaxime
• Excef
• Forax
• Fortax
• Hr 756
• Novatax
• Oritaxim
• Pretor
• Ru 24756
• Sefagen
• Sodium cefotaxime
• Tolycar
• Zafixime
• sodium (6R,7R)-3-[(acetyloxy)methyl]-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

Cefotaxime Sodium

CAS: 64485-93-4

Formula: C₁₆H₁₆N₅NaO₇S₂

Purity: 97.0%

Color and Shape: Solid

Molecular weight: 477.44

Ref: 10-F036515

Cefotaxime sodium - Sterile grade

CAS: 64485-93-4

Cefotaxime sodium - Sterile grade is a cephalosporin antibiotic, which is derived from the beta-lactam class of antibacterial agents. It effectively disrupts bacterial cell wall synthesis by binding to and inhibiting penicillin-binding proteins, leading to cell lysis and death. This mechanism of action is potent against a variety of Gram-positive and Gram-negative bacteria, making it a valuable tool in clinical settings.

Formula: C₁₆H₁₇N₅O₇S₂·Na

Purity: Min. 95%

Molecular weight: 478.46 g/mol

Ref: 3D-AC165016