CAS 645-43-2

Guanethidine monosulfate

Description:

Guanethidine monosulfate is a chemical compound primarily used as an antihypertensive agent. It functions by inhibiting the release of norepinephrine from sympathetic nerve endings, leading to a decrease in blood pressure. The compound is a salt formed from guanethidine and sulfuric acid, which enhances its solubility and stability in aqueous solutions. Guanethidine monosulfate is typically administered in its sulfate form, which is more soluble than its base. The substance is characterized by its crystalline structure and is usually white to off-white in appearance. It has a relatively high melting point and is stable under standard conditions. In terms of safety, guanethidine can cause side effects such as orthostatic hypotension and gastrointestinal disturbances, and its use requires careful monitoring. As with many pharmaceuticals, it is essential to handle guanethidine monosulfate with caution, adhering to safety guidelines to mitigate any potential health risks.

Formula: C₁₀H₂₂N₄·H₂O₄S

InChI: InChI=1S/C10H22N4.H2O4S/c11-10(12)13-6-9-14-7-4-2-1-3-5-8-14;1-5(2,3)4/h1-9H2,(H4,11,12,13);(H2,1,2,3,4)

InChI key: InChIKey=YUFWAVFNITUSHI-UHFFFAOYSA-N

SMILES: S(=O)(=O)(O)O.C(CNC(=N)N)N1CCCCCCC1

Synonyms:

• 1-(2-(Azocan-1-yl)ethyl)guanidine sulfate
• Azocine, guanidine deriv.
• Guanethidine monosulfate
• Guanethidine sulfate (1:1)
• Guanidine, N-[2-(hexahydro-1(2H)-azocinyl)ethyl]-, sulfate (1:1)
• [2-(Hexahydro-(2H)-azocin-1-yl)ethyl]guanidiniumsulfat
• [2-(Hexahydro-1(2H)-azocinyl)ethyl]guanidine hydrogen sulfate
• [2-(hexahydro-(2H)-azocin-1-yl)ethyl]guanidinium sulphate
• sulfate de [2-(hexahydro-(2H)-azocine-1-yl)ethyl]guanidinium
• sulfato de [2-(hexahidro-(2H)-azocin-1-il)etil]guanidinio
• Guanidine, [2-(hexahydro-1(2H)-azocinyl)ethyl]-, sulfate (1:1)

Guanethidine monosulfate

CAS: 645-43-2

Guanethidine monosulfate

Formula: C₁₀H₂₂N₄H₂SO₄

Purity: 99.5%

Color and Shape: White Solid

Molecular weight: 296.15183

Ref: 47-181

Guanethidine Monosulfate

CAS: 645-43-2

Heterocyclic compounds (excluding aromatic or modified

Formula: C₁₀H₂₂N₄·H₂O₄S

Color and Shape: White Powder

Molecular weight: 296.15183

Ref: 45-1301801

Guanethidine sulphate

CAS: 645-43-2

Formula: C₁₀H₂₄N₄O₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 296.3870

Ref: IN-DA00E9HT

Guanethidine Monosulfate

CAS: 645-43-2

Guanethidine Monosulfate

Purity: 98%

Molecular weight: 296.39g/mol

Ref: 54-OR1026642

Guanethidine sulfate

CAS: 645-43-2

Guanethidine sulfate

Purity: ≥98%

Molecular weight: 296.39g/mol

Ref: 54-BUP16093

Guanethidine Monosulfate

CAS: 645-43-2

Formula: C₁₀H₂₂N₄·H₂SO₄

Purity: >97.0%(T)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 296.39

Ref: 3B-G0231

Guanethidine monosulfate

CAS: 645-43-2

Guanethidine monosulfate is an antihypertensive drug that reduces the release of catecholamines.

Formula: C₁₀H₂₄N₄O₄S

Purity: 99.61% - 99.74%

Color and Shape: Solid

Molecular weight: 296.39

Ref: TM-T2575

Guanethidine sulphate

CAS: 645-43-2

Purity: 98.0%

Molecular weight: 296.151826248

Ref: 10-F546220

Guanethidine sulfate

CAS: 645-43-2

Guanethidine sulfate is a drug that belongs to the class of drugs called pressor, which are used in the treatment of high blood pressure. It increases the force and rate of contraction of the heart muscle and has antihypertensive activity. This drug's pharmacokinetic properties have been studied in human serum and tissues from cancerous cells. It has been shown that guanethidine sulfate is absorbed well after oral administration and is excreted rapidly through the kidneys. The drug does not show any significant interactions with other drugs, such as propranolol hydrochloride or estradiol benzoate.

Formula: C₁₀H₂₂N₄•H₂SO₄

Purity: Min. 95%

Color and Shape: Off-White Powder

Molecular weight: 296.39 g/mol

Ref: 3D-FG28830

Guanethidine Monosulfate

Controlled Product

CAS: 645-43-2

Stability Hygroscopic
Applications Guanethidine Monosulfate acts as an antihypertensive; antiglaucoma
References Al-Shora, H., et al.: Int. J. Pharm., 47, 209 (1988), Golander, Y., et al.: J. Pharm. Sci., 77, 902 (1988),

Formula: C₁₀H₂₂N₄·H₂O₄S

Color and Shape: Neat

Molecular weight: 296.39

Ref: TR-G815005