CAS 645-88-5

(Aminooxy)acetic acid

Description:

(Aminooxy)acetic acid, also known as AOAA, is an organic compound characterized by the presence of both amino and oxy functional groups. Its molecular structure features an amino group (-NH2) and a hydroxylamine moiety, which contributes to its reactivity and biological significance. This compound is typically a white to off-white solid and is soluble in water, making it accessible for various applications in biochemical research. AOAA is primarily recognized for its role as an inhibitor of certain enzymes, particularly those involved in the metabolism of neurotransmitters, which has implications in neurochemistry and pharmacology. Its ability to interact with amino acids and other biomolecules allows it to serve as a valuable tool in studying metabolic pathways. Additionally, (Aminooxy)acetic acid is utilized in the synthesis of other chemical compounds and in the development of therapeutic agents. Safety considerations should be taken into account when handling this substance, as it may pose health risks if not managed properly.

Formula: C₂H₅NO₃

InChI: InChI=1S/C2H5NO3/c3-6-1-2(4)5/h1,3H2,(H,4,5)

InChI key: InChIKey=NQRKYASMKDDGHT-UHFFFAOYSA-N

SMILES: C(C(O)=O)ON

Synonyms:

• (Aminooxy)acetic acid
• (Carboxymethoxy)amine
• (O-Carboxymethyl)hydroxylamine
• 2-(Aminooxy)acetic acid
• AOA
• Acetic acid, (aminooxy)-
• Aceticacid, (aminooxy)- (6CI,8CI,9CI)
• Aminoxyacetic acid
• Aoaa
• Hydroxylamine,O-(carboxymethyl)-
• Methoxyamine, 1-carboxy-
• O-(Carboxymethyl)hydroxyamine
• U 7524
• U7524
• a-Aminooxyacetic acid

Acetic acid,2-(aminooxy)-

CAS: 645-88-5

Formula: C₂H₅NO₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 91.0660

Ref: IN-DA006TDP

Aminooxyacetic acid hydrochoride

CAS: 645-88-5

Aminooxyacetic acid hydrochoride is a nitric oxide synthase inhibitor that binds to the active site of the enzyme and prevents it from producing nitric oxide. Nitric oxide is an important molecule in many biological processes, such as vasodilation, neurotransmission, and cell signaling. This inhibitor has been shown to be effective against a number of cancers including prostate cancer cells and breast cancer cells. Aminooxyacetic acid hydrochoride has also been shown to increase the expression of basic proteins in neuronal cells and inhibit DNA synthesis by binding to polymerase chain reaction primers. It also inhibits α7 nicotinic acetylcholine receptors, which are involved in learning and memory. A matrix effect on wild-type strains has been observed when aminooxyacetic acid hydrochloride is added to culture media as well.

Formula: C₂H₄NO₃•HCl

Color and Shape: White Off-White Powder

Molecular weight: 91.07 g/mol

Ref: 3D-FA01375

U-7524

CAS: 645-88-5

U-7524 (AOAA), an inhibitor of GABA-T and other PLP-dependent enzymes, disrupts the Schiff base linkage, forming oxime complexes.

Formula: C₂H₅NO₃

Color and Shape: Solid

Molecular weight: 91.07

Ref: TM-T29033